Angiography-Derived Fractional Flow Reserve in Coronary Assessment: Current Developments and Future Perspectives

Coronary physiology assessment is an important factor in guiding myocardial revascularization. A growing body of research highlights the value of using fractional flow reserve, FFR and other pressure-based indicators for functional assessment of stable coronary stenoses. Invasive functional coronary...

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Main Authors: Han Bing Chow, Shirley Siang Ning Tan, Wei Hong Lai, Alan Yean Yip Fong
Format: Article
Language:English
Published: Compuscript Ltd 2023-04-01
Series:Cardiovascular Innovations and Applications
Online Access:https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2023.0021
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author Han Bing Chow
Shirley Siang Ning Tan
Wei Hong Lai
Alan Yean Yip Fong
author_facet Han Bing Chow
Shirley Siang Ning Tan
Wei Hong Lai
Alan Yean Yip Fong
author_sort Han Bing Chow
collection DOAJ
description Coronary physiology assessment is an important factor in guiding myocardial revascularization. A growing body of research highlights the value of using fractional flow reserve, FFR and other pressure-based indicators for functional assessment of stable coronary stenoses. Invasive functional coronary assessment techniques have evolved from intracoronary wire-based to wire-free approaches as a result of technological advancements. In addition, several software programs on the market have been thoroughly investigated and validated against invasive FFR, and have shown good accuracy and correlation. However, use of FFR remains modest. Hence, this review provides an overview of angiography-based FFR solutions and compares their technologies. Additionally, a systematic scoping review was performed to understand the research landscape in wire-free coronary physiology assessment, to complement the narratives of existing FFR trials on wire-free FFR. Furthermore, future developments and strategies that could expand the use of wire-free computed coronary functional assessment in the Asia Pacific region are discussed.
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spelling doaj.art-bcca1b09a3c14130a622d749c550926c2023-11-25T17:00:20ZengCompuscript LtdCardiovascular Innovations and Applications2009-86182009-87822023-04-018199210.15212/CVIA.2023.0021Angiography-Derived Fractional Flow Reserve in Coronary Assessment: Current Developments and Future PerspectivesHan Bing ChowShirley Siang Ning TanWei Hong LaiAlan Yean Yip FongCoronary physiology assessment is an important factor in guiding myocardial revascularization. A growing body of research highlights the value of using fractional flow reserve, FFR and other pressure-based indicators for functional assessment of stable coronary stenoses. Invasive functional coronary assessment techniques have evolved from intracoronary wire-based to wire-free approaches as a result of technological advancements. In addition, several software programs on the market have been thoroughly investigated and validated against invasive FFR, and have shown good accuracy and correlation. However, use of FFR remains modest. Hence, this review provides an overview of angiography-based FFR solutions and compares their technologies. Additionally, a systematic scoping review was performed to understand the research landscape in wire-free coronary physiology assessment, to complement the narratives of existing FFR trials on wire-free FFR. Furthermore, future developments and strategies that could expand the use of wire-free computed coronary functional assessment in the Asia Pacific region are discussed.https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2023.0021
spellingShingle Han Bing Chow
Shirley Siang Ning Tan
Wei Hong Lai
Alan Yean Yip Fong
Angiography-Derived Fractional Flow Reserve in Coronary Assessment: Current Developments and Future Perspectives
Cardiovascular Innovations and Applications
title Angiography-Derived Fractional Flow Reserve in Coronary Assessment: Current Developments and Future Perspectives
title_full Angiography-Derived Fractional Flow Reserve in Coronary Assessment: Current Developments and Future Perspectives
title_fullStr Angiography-Derived Fractional Flow Reserve in Coronary Assessment: Current Developments and Future Perspectives
title_full_unstemmed Angiography-Derived Fractional Flow Reserve in Coronary Assessment: Current Developments and Future Perspectives
title_short Angiography-Derived Fractional Flow Reserve in Coronary Assessment: Current Developments and Future Perspectives
title_sort angiography derived fractional flow reserve in coronary assessment current developments and future perspectives
url https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2023.0021
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