Uterine leiomyosarcoma and disseminated peritoneal leiomyomatosis in the surgical treatment of uterine myoma: a retrospective analysis
Aim. To analyze the incidence and types of adverse outcomes and complications of laparoscopic myomectomies. Materials and methods. This work is a retrospective study based on data from the Kulakov National Medical Research Center for Obstetrics, Gynecology, and Perinatology. We analyzed 711 case...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | Russian |
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IP Berlin A.V.
2022-11-01
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| Series: | Гинекология |
| Subjects: | |
| Online Access: | https://gynecology.orscience.ru/2079-5831/article/viewFile/110811/pdf |
| _version_ | 1811206257104650240 |
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| author | Alexander A. Seregin Yana A. Kosova Polina A. Seregina Yulia N. Ponomareva Anastasiia B. Nadezhdenskaia Eleonora V. Kirilova Aleksandra V. Asaturova Anna V. Tregubova Alina S. Magnaeva Maria P. Ishchuk Dmitry L. Ovodenko |
| author_facet | Alexander A. Seregin Yana A. Kosova Polina A. Seregina Yulia N. Ponomareva Anastasiia B. Nadezhdenskaia Eleonora V. Kirilova Aleksandra V. Asaturova Anna V. Tregubova Alina S. Magnaeva Maria P. Ishchuk Dmitry L. Ovodenko |
| author_sort | Alexander A. Seregin |
| collection | DOAJ |
| description | Aim. To analyze the incidence and types of adverse outcomes and complications of laparoscopic myomectomies.
Materials and methods. This work is a retrospective study based on data from the Kulakov National Medical Research Center for Obstetrics, Gynecology, and Perinatology. We analyzed 711 case histories of patients diagnosed with uterine myoma who received surgical treatment in the Department of Innovative Oncology and Gynecology from 2015 to 2019. The frequency of malignant neoplasms, verified by pathomorphological examination, and the characteristics of surgical interventions performed in these patients were comparatively evaluated.
Results. Surgical interventions for uterine myoma are leading in gynecology due to the high prevalence of such disorders. Conservative myomectomy remains the "gold standard" in organ-sparing surgery. However, during surgeries for suspected benign neoplasms, there is a risk of morcellation of the malignant tumor, significantly worsening patient survival outcomes. In our study, the incidence of uterine leiomyosarcoma in suspected benign neoplasms was 0.98%. The probability of parasitic myomas or disseminated perineal leiomyomatosis after myomatous nodule morcellation is 0.19%.
Conclusion. No reliable information about the malignant potential of the tumor and its proliferative activity can be obtained until a definitive pathomorphological examination. The above considerations warrant the routine use of prophylactic measures to prevent tumor cell dissemination. |
| first_indexed | 2024-04-12T03:45:28Z |
| format | Article |
| id | doaj.art-bcca3f10fe7a4d58ba0599ef02410937 |
| institution | Directory Open Access Journal |
| issn | 2079-5696 2079-5831 |
| language | Russian |
| last_indexed | 2024-04-12T03:45:28Z |
| publishDate | 2022-11-01 |
| publisher | IP Berlin A.V. |
| record_format | Article |
| series | Гинекология |
| spelling | doaj.art-bcca3f10fe7a4d58ba0599ef024109372022-12-22T03:49:10ZrusIP Berlin A.V.Гинекология2079-56962079-58312022-11-0124538639210.26442/20795696.2022.5.20186079453Uterine leiomyosarcoma and disseminated peritoneal leiomyomatosis in the surgical treatment of uterine myoma: a retrospective analysisAlexander A. Seregin0https://orcid.org/0000-0001-5236-3194Yana A. Kosova1https://orcid.org/0000-0002-4803-2541Polina A. Seregina2https://orcid.org/0000-0001-6149-6212Yulia N. Ponomareva3https://orcid.org/0000-0001-9888-4219Anastasiia B. Nadezhdenskaia4https://orcid.org/0000-0003-0782-5112Eleonora V. Kirilova5https://orcid.org/0000-0002-2793-9814Aleksandra V. Asaturova6https://orcid.org/0000-0001-8739-5209Anna V. Tregubova7https://orcid.org/0000-0003-4601-1330Alina S. Magnaeva8https://orcid.org/0000-0001-5223-9767Maria P. Ishchuk9https://orcid.org/0000-0002-9577-1777Dmitry L. Ovodenko10https://orcid.org/0000-0003-0700-8374Kulakov National Medical Research Center for Obstetrics, Gynecology and PerinatologyYevdokimov Moscow State University of Medicine and DentistrySechenov First Moscow State Medical University (Sechenov University)Kulakov National Medical Research Center for Obstetrics, Gynecology and PerinatologyAstrakhan State Medical UniversityKulakov National Medical Research Center for Obstetrics, Gynecology and PerinatologyKulakov National Medical Research Center for Obstetrics, Gynecology and PerinatologyKulakov National Medical Research Center for Obstetrics, Gynecology and PerinatologyKulakov National Medical Research Center for Obstetrics, Gynecology and PerinatologyKulakov National Medical Research Center for Obstetrics, Gynecology and PerinatologyKulakov National Medical Research Center for Obstetrics, Gynecology and PerinatologyAim. To analyze the incidence and types of adverse outcomes and complications of laparoscopic myomectomies. Materials and methods. This work is a retrospective study based on data from the Kulakov National Medical Research Center for Obstetrics, Gynecology, and Perinatology. We analyzed 711 case histories of patients diagnosed with uterine myoma who received surgical treatment in the Department of Innovative Oncology and Gynecology from 2015 to 2019. The frequency of malignant neoplasms, verified by pathomorphological examination, and the characteristics of surgical interventions performed in these patients were comparatively evaluated. Results. Surgical interventions for uterine myoma are leading in gynecology due to the high prevalence of such disorders. Conservative myomectomy remains the "gold standard" in organ-sparing surgery. However, during surgeries for suspected benign neoplasms, there is a risk of morcellation of the malignant tumor, significantly worsening patient survival outcomes. In our study, the incidence of uterine leiomyosarcoma in suspected benign neoplasms was 0.98%. The probability of parasitic myomas or disseminated perineal leiomyomatosis after myomatous nodule morcellation is 0.19%. Conclusion. No reliable information about the malignant potential of the tumor and its proliferative activity can be obtained until a definitive pathomorphological examination. The above considerations warrant the routine use of prophylactic measures to prevent tumor cell dissemination.https://gynecology.orscience.ru/2079-5831/article/viewFile/110811/pdfuterine myomamorcellationlaparoscopic myomectomymorcellation bagsdisseminated peritoneal leiomyomatosisleiomyosarcoma |
| spellingShingle | Alexander A. Seregin Yana A. Kosova Polina A. Seregina Yulia N. Ponomareva Anastasiia B. Nadezhdenskaia Eleonora V. Kirilova Aleksandra V. Asaturova Anna V. Tregubova Alina S. Magnaeva Maria P. Ishchuk Dmitry L. Ovodenko Uterine leiomyosarcoma and disseminated peritoneal leiomyomatosis in the surgical treatment of uterine myoma: a retrospective analysis Гинекология uterine myoma morcellation laparoscopic myomectomy morcellation bags disseminated peritoneal leiomyomatosis leiomyosarcoma |
| title | Uterine leiomyosarcoma and disseminated peritoneal leiomyomatosis in the surgical treatment of uterine myoma: a retrospective analysis |
| title_full | Uterine leiomyosarcoma and disseminated peritoneal leiomyomatosis in the surgical treatment of uterine myoma: a retrospective analysis |
| title_fullStr | Uterine leiomyosarcoma and disseminated peritoneal leiomyomatosis in the surgical treatment of uterine myoma: a retrospective analysis |
| title_full_unstemmed | Uterine leiomyosarcoma and disseminated peritoneal leiomyomatosis in the surgical treatment of uterine myoma: a retrospective analysis |
| title_short | Uterine leiomyosarcoma and disseminated peritoneal leiomyomatosis in the surgical treatment of uterine myoma: a retrospective analysis |
| title_sort | uterine leiomyosarcoma and disseminated peritoneal leiomyomatosis in the surgical treatment of uterine myoma a retrospective analysis |
| topic | uterine myoma morcellation laparoscopic myomectomy morcellation bags disseminated peritoneal leiomyomatosis leiomyosarcoma |
| url | https://gynecology.orscience.ru/2079-5831/article/viewFile/110811/pdf |
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