Olfactory dysfunction revisited: a reappraisal of work-related olfactory dysfunction caused by chemicals
Abstract Occupational exposure to numerous individual chemicals has been associated with olfactory dysfunction, mainly in individual case descriptions. Comprehensive epidemiological investigations into the olfactotoxic effect of working substances show that the human sense of smell may be impaired b...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2018-09-01
|
Series: | Journal of Occupational Medicine and Toxicology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12995-018-0209-6 |
_version_ | 1811301528699404288 |
---|---|
author | Sabine Werner Eberhard Nies |
author_facet | Sabine Werner Eberhard Nies |
author_sort | Sabine Werner |
collection | DOAJ |
description | Abstract Occupational exposure to numerous individual chemicals has been associated with olfactory dysfunction, mainly in individual case descriptions. Comprehensive epidemiological investigations into the olfactotoxic effect of working substances show that the human sense of smell may be impaired by exposure to metal compounds involving cadmium, chromium and nickel, and to formaldehyde. This conclusion is supported by the results of animal experiments. The level of evidence for a relationship between olfactory dysfunction and workplace exposure to other substances is relatively weak. |
first_indexed | 2024-04-13T07:11:41Z |
format | Article |
id | doaj.art-bcca94cc09724d6084c9e979c30925ce |
institution | Directory Open Access Journal |
issn | 1745-6673 |
language | English |
last_indexed | 2024-04-13T07:11:41Z |
publishDate | 2018-09-01 |
publisher | BMC |
record_format | Article |
series | Journal of Occupational Medicine and Toxicology |
spelling | doaj.art-bcca94cc09724d6084c9e979c30925ce2022-12-22T02:56:52ZengBMCJournal of Occupational Medicine and Toxicology1745-66732018-09-0113112610.1186/s12995-018-0209-6Olfactory dysfunction revisited: a reappraisal of work-related olfactory dysfunction caused by chemicalsSabine Werner0Eberhard Nies1Institute for Occupational Safety and Health of the German Social Accident Insurance, Unit Toxicology of Industrial ChemicalsInstitute for Occupational Safety and Health of the German Social Accident Insurance, Unit Toxicology of Industrial ChemicalsAbstract Occupational exposure to numerous individual chemicals has been associated with olfactory dysfunction, mainly in individual case descriptions. Comprehensive epidemiological investigations into the olfactotoxic effect of working substances show that the human sense of smell may be impaired by exposure to metal compounds involving cadmium, chromium and nickel, and to formaldehyde. This conclusion is supported by the results of animal experiments. The level of evidence for a relationship between olfactory dysfunction and workplace exposure to other substances is relatively weak.http://link.springer.com/article/10.1186/s12995-018-0209-6Chemically induced anosmiaFormaldehydeMetalsOccupational exposureOlfaction disorders |
spellingShingle | Sabine Werner Eberhard Nies Olfactory dysfunction revisited: a reappraisal of work-related olfactory dysfunction caused by chemicals Journal of Occupational Medicine and Toxicology Chemically induced anosmia Formaldehyde Metals Occupational exposure Olfaction disorders |
title | Olfactory dysfunction revisited: a reappraisal of work-related olfactory dysfunction caused by chemicals |
title_full | Olfactory dysfunction revisited: a reappraisal of work-related olfactory dysfunction caused by chemicals |
title_fullStr | Olfactory dysfunction revisited: a reappraisal of work-related olfactory dysfunction caused by chemicals |
title_full_unstemmed | Olfactory dysfunction revisited: a reappraisal of work-related olfactory dysfunction caused by chemicals |
title_short | Olfactory dysfunction revisited: a reappraisal of work-related olfactory dysfunction caused by chemicals |
title_sort | olfactory dysfunction revisited a reappraisal of work related olfactory dysfunction caused by chemicals |
topic | Chemically induced anosmia Formaldehyde Metals Occupational exposure Olfaction disorders |
url | http://link.springer.com/article/10.1186/s12995-018-0209-6 |
work_keys_str_mv | AT sabinewerner olfactorydysfunctionrevisitedareappraisalofworkrelatedolfactorydysfunctioncausedbychemicals AT eberhardnies olfactorydysfunctionrevisitedareappraisalofworkrelatedolfactorydysfunctioncausedbychemicals |