Melatonin increases bone mass in normal, perimenopausal, and postmenopausal osteoporotic rats via the promotion of osteogenesis

Melatonin increases bone mass in normal, perimenopausal, and postmenopausal osteoporotic rats via the promotion of osteogenesis

Abstract Background Osteoporosis is a disease threatening the health of millions of individuals. Melatonin is found to be a potential anti-osteoporosis drug. However, whether melatonin plays a role against osteoporosis at different stages of the menopause and the underlying mechanisms are unknown. M...

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Bibliographic Details
Main Authors: Huanshuai Guan, Ning Kong, Run Tian, Ruomu Cao, Guanzhi Liu, Yiyang Li, Qilu Wei, Ming Jiao, Yutian Lei, Fangze Xing, Peng Tian, Kunzheng Wang, Pei Yang
Format: Article
Language:English
Published: BMC 2022-03-01
Series:Journal of Translational Medicine
Subjects:
Melatonin
Different stages of the menopause
Osteoporosis
Osteogenesis
Bone marrow mesenchymal stem cells
Online Access:https://doi.org/10.1186/s12967-022-03341-7

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