Right heart exercise-training-adaptation and remodelling in endurance athletes
Abstract Long-term sports training leads to myocardial adaptations, with remodelling of the heart chambers. However, while myocardial adaptations of the left heart are well described, remodelling of the right heart and its impact on the development of arrhythmias is still debated. To conduct a syste...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2021-11-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-021-02028-1 |
| _version_ | 1798034799476080640 |
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| author | Valeria Conti Filippo Migliorini Marco Pilone María I. Barriopedro Juan José Ramos-Álvarez Francisco Javer Calderon Montero Nicola Maffulli |
| author_facet | Valeria Conti Filippo Migliorini Marco Pilone María I. Barriopedro Juan José Ramos-Álvarez Francisco Javer Calderon Montero Nicola Maffulli |
| author_sort | Valeria Conti |
| collection | DOAJ |
| description | Abstract Long-term sports training leads to myocardial adaptations, with remodelling of the heart chambers. However, while myocardial adaptations of the left heart are well described, remodelling of the right heart and its impact on the development of arrhythmias is still debated. To conduct a systematic review on right ventricle (RV) and right atrium (RA) structural and functional changes in athletes who participate in long-term endurance training. Systematic review. A systematic literature search was conducted. All the articles reporting right heart echocardiographic (ECHO) and cardiac magnetic resonance (CMR) parameters evaluated in endurance athletes and sedentary subjects were considered eligible. A multivariate analysis was conducted to investigate whether age, sex, body surface area (BSA), intensity of training are associated with RV ECHO, CMR parameters and RA ECHO parameters. A positive association between age and right atrium area (RAA) (P = 0.01) was found. This is a negative association to RV E/A (P = 0.004), and RV end diastolic diameter (RVED) longitudinal (P = 0.01). A positive association between BSA and RVED middle (P = 0.001), as well between BSA and RAA (P = 0.05) was found, along with a negative association with RV E/A (P = 0.002). A positive association between intensity of training and RV end systolic area (RVESA) (P = 0.03), RV end diastolic volume indexed (RVEDVI) (P = 0.01), RV end systolic volume indexed (RVESVI) (P = 0.01) was found, along with a negative association with ejection fraction (EF %) (P = 0.01). Endurance athletes demonstrated an association between RV remodelling and age, BSA and intensity of training. |
| first_indexed | 2024-04-11T20:48:37Z |
| format | Article |
| id | doaj.art-bcccc0a77c164e6892a14c3bebed7ad1 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-11T20:48:37Z |
| publishDate | 2021-11-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-bcccc0a77c164e6892a14c3bebed7ad12022-12-22T04:03:55ZengNature PortfolioScientific Reports2045-23222021-11-0111111210.1038/s41598-021-02028-1Right heart exercise-training-adaptation and remodelling in endurance athletesValeria Conti0Filippo Migliorini1Marco Pilone2María I. Barriopedro3Juan José Ramos-Álvarez4Francisco Javer Calderon Montero5Nicola Maffulli6Department of Medicine, Surgery and Dentistry, University of SalernoDepartment of Orthopaedic, Trauma, and Recontructive Surgery, RWTH Aachen University ClinicDepartment of Medicine, Surgery and Dentistry, University of SalernoFaculty of Physical Activity and Sport Sciences, Universidad Politécnica de MadridEscuela de Medicina Deportiva. Departamento de Radiología, Rehabilitación y Fisioterapia, Universidad Complutense de MadridEscuela de Medicina Deportiva. Departamento de Radiología, Rehabilitación y Fisioterapia, Universidad Complutense de MadridDepartment of Medicine, Surgery and Dentistry, University of SalernoAbstract Long-term sports training leads to myocardial adaptations, with remodelling of the heart chambers. However, while myocardial adaptations of the left heart are well described, remodelling of the right heart and its impact on the development of arrhythmias is still debated. To conduct a systematic review on right ventricle (RV) and right atrium (RA) structural and functional changes in athletes who participate in long-term endurance training. Systematic review. A systematic literature search was conducted. All the articles reporting right heart echocardiographic (ECHO) and cardiac magnetic resonance (CMR) parameters evaluated in endurance athletes and sedentary subjects were considered eligible. A multivariate analysis was conducted to investigate whether age, sex, body surface area (BSA), intensity of training are associated with RV ECHO, CMR parameters and RA ECHO parameters. A positive association between age and right atrium area (RAA) (P = 0.01) was found. This is a negative association to RV E/A (P = 0.004), and RV end diastolic diameter (RVED) longitudinal (P = 0.01). A positive association between BSA and RVED middle (P = 0.001), as well between BSA and RAA (P = 0.05) was found, along with a negative association with RV E/A (P = 0.002). A positive association between intensity of training and RV end systolic area (RVESA) (P = 0.03), RV end diastolic volume indexed (RVEDVI) (P = 0.01), RV end systolic volume indexed (RVESVI) (P = 0.01) was found, along with a negative association with ejection fraction (EF %) (P = 0.01). Endurance athletes demonstrated an association between RV remodelling and age, BSA and intensity of training.https://doi.org/10.1038/s41598-021-02028-1 |
| spellingShingle | Valeria Conti Filippo Migliorini Marco Pilone María I. Barriopedro Juan José Ramos-Álvarez Francisco Javer Calderon Montero Nicola Maffulli Right heart exercise-training-adaptation and remodelling in endurance athletes Scientific Reports |
| title | Right heart exercise-training-adaptation and remodelling in endurance athletes |
| title_full | Right heart exercise-training-adaptation and remodelling in endurance athletes |
| title_fullStr | Right heart exercise-training-adaptation and remodelling in endurance athletes |
| title_full_unstemmed | Right heart exercise-training-adaptation and remodelling in endurance athletes |
| title_short | Right heart exercise-training-adaptation and remodelling in endurance athletes |
| title_sort | right heart exercise training adaptation and remodelling in endurance athletes |
| url | https://doi.org/10.1038/s41598-021-02028-1 |
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