Application of Gene Editing Technology in Resistance Breeding of Livestock
As a new genetic engineering technology, gene editing can precisely modify the specific gene sequence of the organism’s genome. In the last 10 years, with the rapid development of gene editing technology, zinc-finger nucleases (ZFNs), transcription activator-like endonucleases (TALENs), and CRISPR/C...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-07-01
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| Series: | Life |
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| Online Access: | https://www.mdpi.com/2075-1729/12/7/1070 |
| _version_ | 1827628358737854464 |
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| author | Sutian Wang Zixiao Qu Qiuyan Huang Jianfeng Zhang Sen Lin Yecheng Yang Fanming Meng Jianhao Li Kunli Zhang |
| author_facet | Sutian Wang Zixiao Qu Qiuyan Huang Jianfeng Zhang Sen Lin Yecheng Yang Fanming Meng Jianhao Li Kunli Zhang |
| author_sort | Sutian Wang |
| collection | DOAJ |
| description | As a new genetic engineering technology, gene editing can precisely modify the specific gene sequence of the organism’s genome. In the last 10 years, with the rapid development of gene editing technology, zinc-finger nucleases (ZFNs), transcription activator-like endonucleases (TALENs), and CRISPR/Cas9 systems have been applied to modify endogenous genes in organisms accurately. Now, gene editing technology has been used in mice, zebrafish, pigs, cattle, goats, sheep, rabbits, monkeys, and other species. Breeding for disease-resistance in agricultural animals tends to be a difficult task for traditional breeding, but gene editing technology has made this easier. In this work, we overview the development and application of gene editing technology in the resistance breeding of livestock. Also, we further discuss the prospects and outlooks of gene editing technology in disease-resistance breeding. |
| first_indexed | 2024-03-09T13:30:30Z |
| format | Article |
| id | doaj.art-bcceef7a4cdf4ce1ac583fa68cecd739 |
| institution | Directory Open Access Journal |
| issn | 2075-1729 |
| language | English |
| last_indexed | 2024-03-09T13:30:30Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Life |
| spelling | doaj.art-bcceef7a4cdf4ce1ac583fa68cecd7392023-11-30T21:18:26ZengMDPI AGLife2075-17292022-07-01127107010.3390/life12071070Application of Gene Editing Technology in Resistance Breeding of LivestockSutian Wang0Zixiao Qu1Qiuyan Huang2Jianfeng Zhang3Sen Lin4Yecheng Yang5Fanming Meng6Jianhao Li7Kunli Zhang8State Key Laboratory of Livestock and Poultry Breeding, Guangdong Key Laboratory of Animal Breeding and Nutrition, Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, ChinaState Key Laboratory of Livestock and Poultry Breeding, Guangdong Key Laboratory of Animal Breeding and Nutrition, Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, ChinaState Key Laboratory of Livestock and Poultry Breeding, Guangdong Key Laboratory of Animal Breeding and Nutrition, Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, ChinaInstitute of Animal Health, Guangdong Academy of Agricultural Sciences, Guangdong Provincial Key Laboratory of Livestock Disease Prevention Guangdong Province, Guangzhou 510640, ChinaSericultural & Agri-Food Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou 510610, ChinaState Key Laboratory of Livestock and Poultry Breeding, Guangdong Key Laboratory of Animal Breeding and Nutrition, Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, ChinaState Key Laboratory of Livestock and Poultry Breeding, Guangdong Key Laboratory of Animal Breeding and Nutrition, Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, ChinaState Key Laboratory of Livestock and Poultry Breeding, Guangdong Key Laboratory of Animal Breeding and Nutrition, Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, ChinaInstitute of Animal Health, Guangdong Academy of Agricultural Sciences, Guangdong Provincial Key Laboratory of Livestock Disease Prevention Guangdong Province, Guangzhou 510640, ChinaAs a new genetic engineering technology, gene editing can precisely modify the specific gene sequence of the organism’s genome. In the last 10 years, with the rapid development of gene editing technology, zinc-finger nucleases (ZFNs), transcription activator-like endonucleases (TALENs), and CRISPR/Cas9 systems have been applied to modify endogenous genes in organisms accurately. Now, gene editing technology has been used in mice, zebrafish, pigs, cattle, goats, sheep, rabbits, monkeys, and other species. Breeding for disease-resistance in agricultural animals tends to be a difficult task for traditional breeding, but gene editing technology has made this easier. In this work, we overview the development and application of gene editing technology in the resistance breeding of livestock. Also, we further discuss the prospects and outlooks of gene editing technology in disease-resistance breeding.https://www.mdpi.com/2075-1729/12/7/1070genome engineeringlivestock breedingpigscattlesheep |
| spellingShingle | Sutian Wang Zixiao Qu Qiuyan Huang Jianfeng Zhang Sen Lin Yecheng Yang Fanming Meng Jianhao Li Kunli Zhang Application of Gene Editing Technology in Resistance Breeding of Livestock Life genome engineering livestock breeding pigs cattle sheep |
| title | Application of Gene Editing Technology in Resistance Breeding of Livestock |
| title_full | Application of Gene Editing Technology in Resistance Breeding of Livestock |
| title_fullStr | Application of Gene Editing Technology in Resistance Breeding of Livestock |
| title_full_unstemmed | Application of Gene Editing Technology in Resistance Breeding of Livestock |
| title_short | Application of Gene Editing Technology in Resistance Breeding of Livestock |
| title_sort | application of gene editing technology in resistance breeding of livestock |
| topic | genome engineering livestock breeding pigs cattle sheep |
| url | https://www.mdpi.com/2075-1729/12/7/1070 |
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