Meta-analysis of the correlation between pulmonary hypertension and echocardiographic parameters in patients with chronic kidney disease
Objective To investigate the correlation between pulmonary hypertension (PH) and echocardiographic parameters in patients with chronic kidney disease (CKD). Methods PubMed, Embase, Web of Science, Cochrane, VIP, CNKI, and Wanfang databases were systematically searched for articles published from inc...
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| Format: | Article |
| Language: | English |
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PeerJ Inc.
2024-04-01
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| Online Access: | https://peerj.com/articles/17245.pdf |
| _version_ | 1797199010652487680 |
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| author | Jiahui Jin Wen Hao Deqiong Xie |
| author_facet | Jiahui Jin Wen Hao Deqiong Xie |
| author_sort | Jiahui Jin |
| collection | DOAJ |
| description | Objective To investigate the correlation between pulmonary hypertension (PH) and echocardiographic parameters in patients with chronic kidney disease (CKD). Methods PubMed, Embase, Web of Science, Cochrane, VIP, CNKI, and Wanfang databases were systematically searched for articles published from inception to 19 May 2023. Study quality was estimated using the Quality Assessment of Case-Control Studies tool. Forest plots were drawn using R language software. The “metacor” function in the “meta” package was utilized for meta-analysis of the r-values and their standard errors. Heterogeneity and sensitivity analyses were carried out, with the main outcomes as r-value, p-value, and I2 value. Results Eleven studies were included, with 1,809 CKD patients. The correlations between 12 echocardiographic parameters and PH were analyzed. Except for FS and LVEF which were negatively correlated with CKD-PH, the other 10 parameters were positively correlated with CKD-PH. Among them, LA was highly correlated with CKD-PH (0.70 < r < 0.89); LVDD, RA, RV, LVMI, and LVDS were moderately correlated with CKD-PH (0.40 < r < 0.69); while PA, IVS, LVPW, SV, FS, and LVEF were lowly correlated with CKD-PH (0.20 < r < 0.39). The synthesized estimates were stable against heterogeneity. Conclusion CKD-PH patients may have large cardiac chambers, thickened septal tissue on both sides of the chambers, reduced pulmonary artery flow rates, and decreased left ventricular function. |
| first_indexed | 2024-04-24T07:08:57Z |
| format | Article |
| id | doaj.art-bcd16e302f7d497189d78143f8f8ce9b |
| institution | Directory Open Access Journal |
| issn | 2167-8359 |
| language | English |
| last_indexed | 2024-04-24T07:08:57Z |
| publishDate | 2024-04-01 |
| publisher | PeerJ Inc. |
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| series | PeerJ |
| spelling | doaj.art-bcd16e302f7d497189d78143f8f8ce9b2024-04-21T15:05:16ZengPeerJ Inc.PeerJ2167-83592024-04-0112e1724510.7717/peerj.17245Meta-analysis of the correlation between pulmonary hypertension and echocardiographic parameters in patients with chronic kidney diseaseJiahui Jin0Wen Hao1Deqiong Xie2School of Medicine and Life Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaDepartment of Nephrology, Yibin Second People’s Hospital, Yibin, ChinaSchool of Medicine and Life Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaObjective To investigate the correlation between pulmonary hypertension (PH) and echocardiographic parameters in patients with chronic kidney disease (CKD). Methods PubMed, Embase, Web of Science, Cochrane, VIP, CNKI, and Wanfang databases were systematically searched for articles published from inception to 19 May 2023. Study quality was estimated using the Quality Assessment of Case-Control Studies tool. Forest plots were drawn using R language software. The “metacor” function in the “meta” package was utilized for meta-analysis of the r-values and their standard errors. Heterogeneity and sensitivity analyses were carried out, with the main outcomes as r-value, p-value, and I2 value. Results Eleven studies were included, with 1,809 CKD patients. The correlations between 12 echocardiographic parameters and PH were analyzed. Except for FS and LVEF which were negatively correlated with CKD-PH, the other 10 parameters were positively correlated with CKD-PH. Among them, LA was highly correlated with CKD-PH (0.70 < r < 0.89); LVDD, RA, RV, LVMI, and LVDS were moderately correlated with CKD-PH (0.40 < r < 0.69); while PA, IVS, LVPW, SV, FS, and LVEF were lowly correlated with CKD-PH (0.20 < r < 0.39). The synthesized estimates were stable against heterogeneity. Conclusion CKD-PH patients may have large cardiac chambers, thickened septal tissue on both sides of the chambers, reduced pulmonary artery flow rates, and decreased left ventricular function.https://peerj.com/articles/17245.pdfChronic kidney diseasePulmonary hypertensionEchocardiographyMeta-analysis |
| spellingShingle | Jiahui Jin Wen Hao Deqiong Xie Meta-analysis of the correlation between pulmonary hypertension and echocardiographic parameters in patients with chronic kidney disease PeerJ Chronic kidney disease Pulmonary hypertension Echocardiography Meta-analysis |
| title | Meta-analysis of the correlation between pulmonary hypertension and echocardiographic parameters in patients with chronic kidney disease |
| title_full | Meta-analysis of the correlation between pulmonary hypertension and echocardiographic parameters in patients with chronic kidney disease |
| title_fullStr | Meta-analysis of the correlation between pulmonary hypertension and echocardiographic parameters in patients with chronic kidney disease |
| title_full_unstemmed | Meta-analysis of the correlation between pulmonary hypertension and echocardiographic parameters in patients with chronic kidney disease |
| title_short | Meta-analysis of the correlation between pulmonary hypertension and echocardiographic parameters in patients with chronic kidney disease |
| title_sort | meta analysis of the correlation between pulmonary hypertension and echocardiographic parameters in patients with chronic kidney disease |
| topic | Chronic kidney disease Pulmonary hypertension Echocardiography Meta-analysis |
| url | https://peerj.com/articles/17245.pdf |
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