Hepatitis C Virus Infection in the Patients with Type 2 Diabetes Mellitus
The association of hepatitis C virus (HCV) infection with diabetes mellitus (DM) is a well documented topic. However, it has been debated whether HCV infection is the additional risk factor for the development of DM or it is an associated disease. To determine the prevalence of HCV infection and ass...
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Bilimsel Tip Yayinevi
2003-12-01
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Series: | Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi |
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Online Access: | http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2003-8-4-297-301.pdf |
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author | Serpil EROL İlyas ÇAPOĞLU Halil YAZGI Ömer YILMAZ Ayten KADANALI |
author_facet | Serpil EROL İlyas ÇAPOĞLU Halil YAZGI Ömer YILMAZ Ayten KADANALI |
author_sort | Serpil EROL |
collection | DOAJ |
description | The association of hepatitis C virus (HCV) infection with diabetes mellitus (DM) is a well documented topic. However, it has been debated whether HCV infection is the additional risk factor for the development of DM or it is an associated disease. To determine the prevalence of HCV infection and associated risk factors in diabetic patients, we investigated anti-HCV antibody in the 207 patients with DM (mean age: 58.9 ± 9.3, range 38-85) and 254 control subjects (mean age: 54.0 ± 9.7, range 40-81) by ELISA method, and risk factors for HCV infection in diabetic patients. Statistical analysis was performed by chi-square test, t-test and
logistic regression analysis. Anti-HCV was found positive in 16 (7.7%) of diabetic cases and 5 (2.0%) of the control subjects. According to this result, a higher seroprevalence of HCV infection was observed in patients with type 2 DM (p= 0.003). We did not detect any difference between anti-HCV positive and negative
patients with respect to age, sex, duration of diabetes, hospital admission, mode of therapy and known risk factors for HCV infection (p> 0.05) whereas mean ALT levels was higher in anti-HCV positive patients (p= 0.05). The results of this study suggest that HCV infection in the diabetic patients seems a trigger factor rather than to be an associated disease. |
first_indexed | 2024-04-10T11:12:48Z |
format | Article |
id | doaj.art-bcd276a5fe434aa7ba9dd3f8f222232c |
institution | Directory Open Access Journal |
issn | 1300-932X 1300-932X |
language | English |
last_indexed | 2024-04-10T11:12:48Z |
publishDate | 2003-12-01 |
publisher | Bilimsel Tip Yayinevi |
record_format | Article |
series | Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi |
spelling | doaj.art-bcd276a5fe434aa7ba9dd3f8f222232c2023-02-15T16:18:59ZengBilimsel Tip YayineviFlora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi1300-932X1300-932X2003-12-0184297301Hepatitis C Virus Infection in the Patients with Type 2 Diabetes MellitusSerpil EROL0İlyas ÇAPOĞLU1Halil YAZGI2Ömer YILMAZ3Ayten KADANALI4Atatürk Üniversitesi Tıp Fakültesi, Klinik Bakteriyoloji ve İnfeksiyon Hastalıkları Anabilim DalıAtatürk Üniversitesi Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Endokrinoloji ve Metabolizma Hastalıkları Bilim DalıAtatürk Üniversitesi Tıp Fakültesi, Mikrobiyoloji ve Klinik Mikrobiyoloji Anabilim Dalı,Atatürk Üniversitesi Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, ERZURUMAtatürk Üniversitesi Tıp Fakültesi, Klinik Bakteriyoloji ve İnfeksiyon Hastalıkları Anabilim DalıThe association of hepatitis C virus (HCV) infection with diabetes mellitus (DM) is a well documented topic. However, it has been debated whether HCV infection is the additional risk factor for the development of DM or it is an associated disease. To determine the prevalence of HCV infection and associated risk factors in diabetic patients, we investigated anti-HCV antibody in the 207 patients with DM (mean age: 58.9 ± 9.3, range 38-85) and 254 control subjects (mean age: 54.0 ± 9.7, range 40-81) by ELISA method, and risk factors for HCV infection in diabetic patients. Statistical analysis was performed by chi-square test, t-test and logistic regression analysis. Anti-HCV was found positive in 16 (7.7%) of diabetic cases and 5 (2.0%) of the control subjects. According to this result, a higher seroprevalence of HCV infection was observed in patients with type 2 DM (p= 0.003). We did not detect any difference between anti-HCV positive and negative patients with respect to age, sex, duration of diabetes, hospital admission, mode of therapy and known risk factors for HCV infection (p> 0.05) whereas mean ALT levels was higher in anti-HCV positive patients (p= 0.05). The results of this study suggest that HCV infection in the diabetic patients seems a trigger factor rather than to be an associated disease.http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2003-8-4-297-301.pdfHepatitis C virusDiabetes mellitusPrevalenceRisk |
spellingShingle | Serpil EROL İlyas ÇAPOĞLU Halil YAZGI Ömer YILMAZ Ayten KADANALI Hepatitis C Virus Infection in the Patients with Type 2 Diabetes Mellitus Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi Hepatitis C virus Diabetes mellitus Prevalence Risk |
title | Hepatitis C Virus Infection in the Patients with Type 2 Diabetes Mellitus |
title_full | Hepatitis C Virus Infection in the Patients with Type 2 Diabetes Mellitus |
title_fullStr | Hepatitis C Virus Infection in the Patients with Type 2 Diabetes Mellitus |
title_full_unstemmed | Hepatitis C Virus Infection in the Patients with Type 2 Diabetes Mellitus |
title_short | Hepatitis C Virus Infection in the Patients with Type 2 Diabetes Mellitus |
title_sort | hepatitis c virus infection in the patients with type 2 diabetes mellitus |
topic | Hepatitis C virus Diabetes mellitus Prevalence Risk |
url | http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2003-8-4-297-301.pdf |
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