Hepatitis C Virus Infection in the Patients with Type 2 Diabetes Mellitus

The association of hepatitis C virus (HCV) infection with diabetes mellitus (DM) is a well documented topic. However, it has been debated whether HCV infection is the additional risk factor for the development of DM or it is an associated disease. To determine the prevalence of HCV infection and ass...

Full description

Bibliographic Details
Main Authors: Serpil EROL, İlyas ÇAPOĞLU, Halil YAZGI, Ömer YILMAZ, Ayten KADANALI
Format: Article
Language:English
Published: Bilimsel Tip Yayinevi 2003-12-01
Series:Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Subjects:
Online Access:http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2003-8-4-297-301.pdf
_version_ 1797909711479111680
author Serpil EROL
İlyas ÇAPOĞLU
Halil YAZGI
Ömer YILMAZ
Ayten KADANALI
author_facet Serpil EROL
İlyas ÇAPOĞLU
Halil YAZGI
Ömer YILMAZ
Ayten KADANALI
author_sort Serpil EROL
collection DOAJ
description The association of hepatitis C virus (HCV) infection with diabetes mellitus (DM) is a well documented topic. However, it has been debated whether HCV infection is the additional risk factor for the development of DM or it is an associated disease. To determine the prevalence of HCV infection and associated risk factors in diabetic patients, we investigated anti-HCV antibody in the 207 patients with DM (mean age: 58.9 ± 9.3, range 38-85) and 254 control subjects (mean age: 54.0 ± 9.7, range 40-81) by ELISA method, and risk factors for HCV infection in diabetic patients. Statistical analysis was performed by chi-square test, t-test and logistic regression analysis. Anti-HCV was found positive in 16 (7.7%) of diabetic cases and 5 (2.0%) of the control subjects. According to this result, a higher seroprevalence of HCV infection was observed in patients with type 2 DM (p= 0.003). We did not detect any difference between anti-HCV positive and negative patients with respect to age, sex, duration of diabetes, hospital admission, mode of therapy and known risk factors for HCV infection (p> 0.05) whereas mean ALT levels was higher in anti-HCV positive patients (p= 0.05). The results of this study suggest that HCV infection in the diabetic patients seems a trigger factor rather than to be an associated disease.
first_indexed 2024-04-10T11:12:48Z
format Article
id doaj.art-bcd276a5fe434aa7ba9dd3f8f222232c
institution Directory Open Access Journal
issn 1300-932X
1300-932X
language English
last_indexed 2024-04-10T11:12:48Z
publishDate 2003-12-01
publisher Bilimsel Tip Yayinevi
record_format Article
series Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
spelling doaj.art-bcd276a5fe434aa7ba9dd3f8f222232c2023-02-15T16:18:59ZengBilimsel Tip YayineviFlora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi1300-932X1300-932X2003-12-0184297301Hepatitis C Virus Infection in the Patients with Type 2 Diabetes MellitusSerpil EROL0İlyas ÇAPOĞLU1Halil YAZGI2Ömer YILMAZ3Ayten KADANALI4Atatürk Üniversitesi Tıp Fakültesi, Klinik Bakteriyoloji ve İnfeksiyon Hastalıkları Anabilim DalıAtatürk Üniversitesi Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Endokrinoloji ve Metabolizma Hastalıkları Bilim DalıAtatürk Üniversitesi Tıp Fakültesi, Mikrobiyoloji ve Klinik Mikrobiyoloji Anabilim Dalı,Atatürk Üniversitesi Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, ERZURUMAtatürk Üniversitesi Tıp Fakültesi, Klinik Bakteriyoloji ve İnfeksiyon Hastalıkları Anabilim DalıThe association of hepatitis C virus (HCV) infection with diabetes mellitus (DM) is a well documented topic. However, it has been debated whether HCV infection is the additional risk factor for the development of DM or it is an associated disease. To determine the prevalence of HCV infection and associated risk factors in diabetic patients, we investigated anti-HCV antibody in the 207 patients with DM (mean age: 58.9 ± 9.3, range 38-85) and 254 control subjects (mean age: 54.0 ± 9.7, range 40-81) by ELISA method, and risk factors for HCV infection in diabetic patients. Statistical analysis was performed by chi-square test, t-test and logistic regression analysis. Anti-HCV was found positive in 16 (7.7%) of diabetic cases and 5 (2.0%) of the control subjects. According to this result, a higher seroprevalence of HCV infection was observed in patients with type 2 DM (p= 0.003). We did not detect any difference between anti-HCV positive and negative patients with respect to age, sex, duration of diabetes, hospital admission, mode of therapy and known risk factors for HCV infection (p> 0.05) whereas mean ALT levels was higher in anti-HCV positive patients (p= 0.05). The results of this study suggest that HCV infection in the diabetic patients seems a trigger factor rather than to be an associated disease.http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2003-8-4-297-301.pdfHepatitis C virusDiabetes mellitusPrevalenceRisk
spellingShingle Serpil EROL
İlyas ÇAPOĞLU
Halil YAZGI
Ömer YILMAZ
Ayten KADANALI
Hepatitis C Virus Infection in the Patients with Type 2 Diabetes Mellitus
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Hepatitis C virus
Diabetes mellitus
Prevalence
Risk
title Hepatitis C Virus Infection in the Patients with Type 2 Diabetes Mellitus
title_full Hepatitis C Virus Infection in the Patients with Type 2 Diabetes Mellitus
title_fullStr Hepatitis C Virus Infection in the Patients with Type 2 Diabetes Mellitus
title_full_unstemmed Hepatitis C Virus Infection in the Patients with Type 2 Diabetes Mellitus
title_short Hepatitis C Virus Infection in the Patients with Type 2 Diabetes Mellitus
title_sort hepatitis c virus infection in the patients with type 2 diabetes mellitus
topic Hepatitis C virus
Diabetes mellitus
Prevalence
Risk
url http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2003-8-4-297-301.pdf
work_keys_str_mv AT serpilerol hepatitiscvirusinfectioninthepatientswithtype2diabetesmellitus
AT ilyascapoglu hepatitiscvirusinfectioninthepatientswithtype2diabetesmellitus
AT halilyazgi hepatitiscvirusinfectioninthepatientswithtype2diabetesmellitus
AT omeryilmaz hepatitiscvirusinfectioninthepatientswithtype2diabetesmellitus
AT aytenkadanali hepatitiscvirusinfectioninthepatientswithtype2diabetesmellitus