Repeatability, reproducibility and interocular difference in the assessments of optic nerve OCT in children– a Swedish population-based study

Abstract Background The aim was, first, to collect normative data of the optic nerve head and the peripapillary retinal nerve fibre layer (RNFL) thickness assessed with Cirrus SD-OCT, in healthy children in a population-based study; second, using these data, to examine repeatability, reproducibility...

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Main Authors: Eva Larsson, Anna Molnar, Gerd Holmström
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Ophthalmology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12886-018-0940-x
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author Eva Larsson
Anna Molnar
Gerd Holmström
author_facet Eva Larsson
Anna Molnar
Gerd Holmström
author_sort Eva Larsson
collection DOAJ
description Abstract Background The aim was, first, to collect normative data of the optic nerve head and the peripapillary retinal nerve fibre layer (RNFL) thickness assessed with Cirrus SD-OCT, in healthy children in a population-based study; second, using these data, to examine repeatability, reproducibility and the interocular difference. Methods One-hundred and ten eyes from 57 children aged 6–15 born at term, were examined. Best-corrected visual acuity and refraction were assessed. Both eyes were examined and the interocular difference was calculated. Repeatability was calculated by one examiner performing three assessments. Thereafter, a second examiner repeated the assessments to calculate reproducibility. Results Mean RNFL thickness was 99.2 (SD 8.8) μm, mean disc area 1.89 (SD 0.37) mm2 and mean rim area 1.52 (SD 0.26) mm2. No significant correlations with age, gender or refraction were found. Repeatability and reproducibility were good overall. There was interocular symmetry between the eyes. Conclusions Normal values for optic nerve head and RNFL thickness assessed with Cirrus SD-OCT were gathered to obtain a normal material in children. High repeatability and reproducibility indicated reliability of assessments performed by different examiners on different occasions. Overall, good correlation between right and left eyes was found.
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spelling doaj.art-bcd5933b5dd84e2e85fe10674e01db262022-12-22T03:54:31ZengBMCBMC Ophthalmology1471-24152018-10-011811610.1186/s12886-018-0940-xRepeatability, reproducibility and interocular difference in the assessments of optic nerve OCT in children– a Swedish population-based studyEva Larsson0Anna Molnar1Gerd Holmström2Department of Neuroscience/Ophthalmology, Uppsala UniversityDepartment of Neuroscience/Ophthalmology, Uppsala UniversityDepartment of Neuroscience/Ophthalmology, Uppsala UniversityAbstract Background The aim was, first, to collect normative data of the optic nerve head and the peripapillary retinal nerve fibre layer (RNFL) thickness assessed with Cirrus SD-OCT, in healthy children in a population-based study; second, using these data, to examine repeatability, reproducibility and the interocular difference. Methods One-hundred and ten eyes from 57 children aged 6–15 born at term, were examined. Best-corrected visual acuity and refraction were assessed. Both eyes were examined and the interocular difference was calculated. Repeatability was calculated by one examiner performing three assessments. Thereafter, a second examiner repeated the assessments to calculate reproducibility. Results Mean RNFL thickness was 99.2 (SD 8.8) μm, mean disc area 1.89 (SD 0.37) mm2 and mean rim area 1.52 (SD 0.26) mm2. No significant correlations with age, gender or refraction were found. Repeatability and reproducibility were good overall. There was interocular symmetry between the eyes. Conclusions Normal values for optic nerve head and RNFL thickness assessed with Cirrus SD-OCT were gathered to obtain a normal material in children. High repeatability and reproducibility indicated reliability of assessments performed by different examiners on different occasions. Overall, good correlation between right and left eyes was found.http://link.springer.com/article/10.1186/s12886-018-0940-xOptical coherence tomography (OCT)ChildrenNormal valuesRepeatabilityReproducibilityInterocular difference
spellingShingle Eva Larsson
Anna Molnar
Gerd Holmström
Repeatability, reproducibility and interocular difference in the assessments of optic nerve OCT in children– a Swedish population-based study
BMC Ophthalmology
Optical coherence tomography (OCT)
Children
Normal values
Repeatability
Reproducibility
Interocular difference
title Repeatability, reproducibility and interocular difference in the assessments of optic nerve OCT in children– a Swedish population-based study
title_full Repeatability, reproducibility and interocular difference in the assessments of optic nerve OCT in children– a Swedish population-based study
title_fullStr Repeatability, reproducibility and interocular difference in the assessments of optic nerve OCT in children– a Swedish population-based study
title_full_unstemmed Repeatability, reproducibility and interocular difference in the assessments of optic nerve OCT in children– a Swedish population-based study
title_short Repeatability, reproducibility and interocular difference in the assessments of optic nerve OCT in children– a Swedish population-based study
title_sort repeatability reproducibility and interocular difference in the assessments of optic nerve oct in children a swedish population based study
topic Optical coherence tomography (OCT)
Children
Normal values
Repeatability
Reproducibility
Interocular difference
url http://link.springer.com/article/10.1186/s12886-018-0940-x
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