Management of Spontaneous Aortic Thrombus Following Cisplatin-Based Chemotherapy in Urothelial Cancer: A Case Report

Spontaneous aortic thrombosis is exceedingly rare, and optimal treatment remains uncertain. We present an unusual case of a spontaneous aortic thrombus at the renal artery level in a patient undergoing active cisplatin treatment for urothelial carcinoma. Management included catheter-directed thrombo...

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Main Authors: Victoria Meijia Zheng, Yun Le Linn, Jack Kian Ch’ng, Siew Ping Chng
Format: Article
Language:English
Published: Medrang 2023-12-01
Series:Vascular Specialist International
Subjects:
Online Access:http://www.vsijournal.org/journal/view.html?doi=10.5758/vsi.230091
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author Victoria Meijia Zheng
Yun Le Linn
Jack Kian Ch’ng
Siew Ping Chng
author_facet Victoria Meijia Zheng
Yun Le Linn
Jack Kian Ch’ng
Siew Ping Chng
author_sort Victoria Meijia Zheng
collection DOAJ
description Spontaneous aortic thrombosis is exceedingly rare, and optimal treatment remains uncertain. We present an unusual case of a spontaneous aortic thrombus at the renal artery level in a patient undergoing active cisplatin treatment for urothelial carcinoma. Management included catheter-directed thrombolysis followed by thrombectomy. An open cutdown was performed on the left common femoral artery (CFA), with right groin access via a 6-Fr sheath. Clamping of the left superficial and deep femoral arteries, along with balloon occlusion of the right common iliac artery, prevented distal embolization. A Coda balloon introduced via direct left CFA puncture with a 20-Fr sheath was positioned above the aortic thrombus. After inflation, clots were trawled to the sheath, “sandwiching” the clots before removal of the balloon and sheath via the left groin. Post-operatively, the patient recovered well and received continued therapeutic anticoagulation.
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spelling doaj.art-bcd5b2dce3724a4390fc2e6fc0979ada2023-12-19T00:19:41ZengMedrangVascular Specialist International2288-79702288-79892023-12-013910.5758/vsi.230091vsi.230091Management of Spontaneous Aortic Thrombus Following Cisplatin-Based Chemotherapy in Urothelial Cancer: A Case ReportVictoria Meijia Zheng0Yun Le Linn1Jack Kian Ch’ng2Siew Ping Chng3Yong Loo Lin School of Medicine, National University of Singapore, SingaporeDepartment of Vascular Surgery, Singapore General Hospital, SingaporeDepartment of Vascular Surgery, Singapore General Hospital, SingaporeDepartment of Vascular Surgery, Singapore General Hospital, SingaporeSpontaneous aortic thrombosis is exceedingly rare, and optimal treatment remains uncertain. We present an unusual case of a spontaneous aortic thrombus at the renal artery level in a patient undergoing active cisplatin treatment for urothelial carcinoma. Management included catheter-directed thrombolysis followed by thrombectomy. An open cutdown was performed on the left common femoral artery (CFA), with right groin access via a 6-Fr sheath. Clamping of the left superficial and deep femoral arteries, along with balloon occlusion of the right common iliac artery, prevented distal embolization. A Coda balloon introduced via direct left CFA puncture with a 20-Fr sheath was positioned above the aortic thrombus. After inflation, clots were trawled to the sheath, “sandwiching” the clots before removal of the balloon and sheath via the left groin. Post-operatively, the patient recovered well and received continued therapeutic anticoagulation.http://www.vsijournal.org/journal/view.html?doi=10.5758/vsi.230091thrombusabdominal aortathrombectomy
spellingShingle Victoria Meijia Zheng
Yun Le Linn
Jack Kian Ch’ng
Siew Ping Chng
Management of Spontaneous Aortic Thrombus Following Cisplatin-Based Chemotherapy in Urothelial Cancer: A Case Report
Vascular Specialist International
thrombus
abdominal aorta
thrombectomy
title Management of Spontaneous Aortic Thrombus Following Cisplatin-Based Chemotherapy in Urothelial Cancer: A Case Report
title_full Management of Spontaneous Aortic Thrombus Following Cisplatin-Based Chemotherapy in Urothelial Cancer: A Case Report
title_fullStr Management of Spontaneous Aortic Thrombus Following Cisplatin-Based Chemotherapy in Urothelial Cancer: A Case Report
title_full_unstemmed Management of Spontaneous Aortic Thrombus Following Cisplatin-Based Chemotherapy in Urothelial Cancer: A Case Report
title_short Management of Spontaneous Aortic Thrombus Following Cisplatin-Based Chemotherapy in Urothelial Cancer: A Case Report
title_sort management of spontaneous aortic thrombus following cisplatin based chemotherapy in urothelial cancer a case report
topic thrombus
abdominal aorta
thrombectomy
url http://www.vsijournal.org/journal/view.html?doi=10.5758/vsi.230091
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