Management of Pelvic Pain in Patients with Crohn’s Disease—Current Overview
Crohn’s disease (CD) is a subtype of chronic inflammatory bowel diseases (IBD) with characteristic skip lesions and transmural inflammation that may affect the entire gastrointestinal tract from the mouth to the anus. Persistent pain is one of the main symptoms of CD. This pain has multifactorial pa...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-01-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/12/2/526 |
| _version_ | 1797440700475768832 |
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| author | Jakub Włodarczyk Jacek Burzyński Bartłomiej Czerwiński Mateusz Prusisz Katarzyna Socała Ewa Poleszak Jakub Fichna Kasper Maryńczak Marcin Włodarczyk Łukasz Dziki |
| author_facet | Jakub Włodarczyk Jacek Burzyński Bartłomiej Czerwiński Mateusz Prusisz Katarzyna Socała Ewa Poleszak Jakub Fichna Kasper Maryńczak Marcin Włodarczyk Łukasz Dziki |
| author_sort | Jakub Włodarczyk |
| collection | DOAJ |
| description | Crohn’s disease (CD) is a subtype of chronic inflammatory bowel diseases (IBD) with characteristic skip lesions and transmural inflammation that may affect the entire gastrointestinal tract from the mouth to the anus. Persistent pain is one of the main symptoms of CD. This pain has multifactorial pathogenesis, but most often arises from intestinal inflammation itself, as well as from gut distention or partial intestinal obstruction. Some current evidence also suggests sensitization of sensory pathways, as well as modulation of those signals by the central nervous system, which highlights the impact of biopsychosocial factors. To date, most studies have focused only on the pain located in the abdomen, while pelvic pain has rarely been explored, despite it being a common symptom. The aim of this study is to provide an abbreviated summary of the current state of knowledge on the origins and treatment of pelvic pain in CD. |
| first_indexed | 2024-03-09T12:12:06Z |
| format | Article |
| id | doaj.art-bcd5ef5ec2ee4ed6a776b86d090672f9 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-09T12:12:06Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-bcd5ef5ec2ee4ed6a776b86d090672f92023-11-30T22:51:09ZengMDPI AGJournal of Clinical Medicine2077-03832023-01-0112252610.3390/jcm12020526Management of Pelvic Pain in Patients with Crohn’s Disease—Current OverviewJakub Włodarczyk0Jacek Burzyński1Bartłomiej Czerwiński2Mateusz Prusisz3Katarzyna Socała4Ewa Poleszak5Jakub Fichna6Kasper Maryńczak7Marcin Włodarczyk8Łukasz Dziki9Department of General and Oncological, Medical University of Lodz, Pomorska 251, 90-213 Lodz, PolandDepartment of General and Oncological, Medical University of Lodz, Pomorska 251, 90-213 Lodz, PolandDepartment of General and Oncological, Medical University of Lodz, Pomorska 251, 90-213 Lodz, PolandDepartment of General and Oncological, Medical University of Lodz, Pomorska 251, 90-213 Lodz, PolandDepartment of Animal Physiology and Pharmacology, Institute of Biological Sciences, Maria Curie-Skłodowska University, Akademicka 19, 20-033 Lublin, PolandChair and Department of Applied and Social Pharmacy, Medical University of Lublin, Chodźki 1, 20-093 Lublin, PolandDepartment of Biochemistry, Medical University of Lodz, Mazowiecka 6/8, 92-215 Lodz, PolandDepartment of General and Oncological, Medical University of Lodz, Pomorska 251, 90-213 Lodz, PolandDepartment of General and Oncological, Medical University of Lodz, Pomorska 251, 90-213 Lodz, PolandDepartment of General and Oncological, Medical University of Lodz, Pomorska 251, 90-213 Lodz, PolandCrohn’s disease (CD) is a subtype of chronic inflammatory bowel diseases (IBD) with characteristic skip lesions and transmural inflammation that may affect the entire gastrointestinal tract from the mouth to the anus. Persistent pain is one of the main symptoms of CD. This pain has multifactorial pathogenesis, but most often arises from intestinal inflammation itself, as well as from gut distention or partial intestinal obstruction. Some current evidence also suggests sensitization of sensory pathways, as well as modulation of those signals by the central nervous system, which highlights the impact of biopsychosocial factors. To date, most studies have focused only on the pain located in the abdomen, while pelvic pain has rarely been explored, despite it being a common symptom. The aim of this study is to provide an abbreviated summary of the current state of knowledge on the origins and treatment of pelvic pain in CD.https://www.mdpi.com/2077-0383/12/2/526Crohn’s diseasepelvic painpain treatmentpelvic manifestations of Crohn’s disease |
| spellingShingle | Jakub Włodarczyk Jacek Burzyński Bartłomiej Czerwiński Mateusz Prusisz Katarzyna Socała Ewa Poleszak Jakub Fichna Kasper Maryńczak Marcin Włodarczyk Łukasz Dziki Management of Pelvic Pain in Patients with Crohn’s Disease—Current Overview Journal of Clinical Medicine Crohn’s disease pelvic pain pain treatment pelvic manifestations of Crohn’s disease |
| title | Management of Pelvic Pain in Patients with Crohn’s Disease—Current Overview |
| title_full | Management of Pelvic Pain in Patients with Crohn’s Disease—Current Overview |
| title_fullStr | Management of Pelvic Pain in Patients with Crohn’s Disease—Current Overview |
| title_full_unstemmed | Management of Pelvic Pain in Patients with Crohn’s Disease—Current Overview |
| title_short | Management of Pelvic Pain in Patients with Crohn’s Disease—Current Overview |
| title_sort | management of pelvic pain in patients with crohn s disease current overview |
| topic | Crohn’s disease pelvic pain pain treatment pelvic manifestations of Crohn’s disease |
| url | https://www.mdpi.com/2077-0383/12/2/526 |
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