One-Pot Multicomponent Synthesis and Cytotoxic Evaluation of Novel 7-Substituted-5-(1<i>H</i>-Indol-3-yl)Tetrazolo[1,5-a] Pyrimidine-6-Carbonitrile

One-Pot Multicomponent Synthesis and Cytotoxic Evaluation of Novel 7-Substituted-5-(1<i>H</i>-Indol-3-yl)Tetrazolo[1,5-a] Pyrimidine-6-Carbonitrile

A series of novel 7-substituted-5-(1<i>H</i>-indol-3-<i>yl</i>)tetrazolo[1,5-a]pyrimidine-6-carbonitrile was synthesized via a one-pot, three-multicomponent reaction of appropriate aldehydes, 1<i>H</i>-tetrazole-5-amine and 3-cyanoacetyl indole in catalytic trieth...

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Bibliographic Details
Main Authors:	Mohamed A. A. Radwan, Fahad M. Alminderej, Hanem M. Awad
Format:	Article
Language:	English
Published:	MDPI AG 2020-01-01
Series:	Molecules
Subjects:	indole tetrazole pyrimidine multicomponent reaction (mcrs) cytotoxicity hct-116 mcf-7 mda-mb-231 a549
Online Access:	https://www.mdpi.com/1420-3049/25/2/255

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