A hybrid deep forest-based method for predicting synergistic drug combinations

A hybrid deep forest-based method for predicting synergistic drug combinations

Summary: Combination therapy is a promising approach in treating multiple complex diseases. However, the large search space of available drug combinations exacerbates challenge for experimental screening. To predict synergistic drug combinations in different cancer cell lines, we propose an improved...

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Bibliographic Details
Main Authors:	Lianlian Wu, Jie Gao, Yixin Zhang, Binsheng Sui, Yuqi Wen, Qingqiang Wu, Kunhong Liu, Song He, Xiaochen Bo
Format:	Article
Language:	English
Published:	Elsevier 2023-02-01
Series:	Cell Reports: Methods
Subjects:	CP: Systems biology
Online Access:	http://www.sciencedirect.com/science/article/pii/S266723752300022X

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