The incidence of depressive disorders in patients with schizophrenia

Summary. Introduction. Historically, depressive disorders have been described in various forms of schizophrenia by Kraepelin (1923) or as a reaction to illness by Bleuler (1922). One of the alternative points of view that has been considered in recent years is that depressive disorders are a comorbi...

Full description

Bibliographic Details
Main Authors: M. A. Novitskiy, N. A. Shnayder, R. F. Nasyrova
Format: Article
Language:Russian
Published: Federal State Budget Scientific Institution National Medical Research Center for Psychiatry and Neurology n.a. V.M. Bekhterev Ministry of Health of the Russian Federation 2021-10-01
Series:Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева
Subjects:
Online Access:https://www.bekhterevreview.com/jour/article/view/584
_version_ 1826573067450580992
author M. A. Novitskiy
N. A. Shnayder
R. F. Nasyrova
author_facet M. A. Novitskiy
N. A. Shnayder
R. F. Nasyrova
author_sort M. A. Novitskiy
collection DOAJ
description Summary. Introduction. Historically, depressive disorders have been described in various forms of schizophrenia by Kraepelin (1923) or as a reaction to illness by Bleuler (1922). One of the alternative points of view that has been considered in recent years is that depressive disorders are a comorbid condition of schizophrenia or one of the manifestations of schizophrenia. However, to date, depression, as a symptom, is not included in the diagnostic criteria of the ICD-10. Methodological approaches to diagnosing depressive disorders in patients with schizophrenia differ in different countries and research groups. This influences the prevalence rates of depressive disorders in schizophrenic patients. Purpose. The study and systematization of studies of the incidence of depressive disorders in patients with schizophrenia.Methods. Russian-language and foreign literature was analyzed with a search depth of 10 years (2010–2020) in the following databases: PubMed, Springer, Wiley Online Library, Taylor & Francis Online, US National Library of Medicine National Institutes of Health, Science Direct and eLIBRARY .RU.Results. A total of 51 studies of depressive disorders in children and adults with schizophrenia were found.Conclusion. The frequency of occurrence of depressive disorders in patients with schizophrenia varies from 9.1 and to 100%, the average frequency is 41.6%. Their frequency is variable and depends on the region of residence and ethnicity. It is noted that depressive disorders in patients with schizophrenia are more often recorded among residents of the Middle East (72.7%), Russia (61.8%) and Europe (39.6%), less often among residents of Southeast Asia (32%) and the Pacific region ( 37.3%). The countries with the highest incidence of depressive disorders in schizophrenia include: USA, Germany, China; and to the countries with the lowest frequency — Denmark, Israel, South Africa. Also, I would like to note that the largest number of studies conducted was in Europe (16 studies with 36 928 patients with schizophrenia), the USA (6 studies with 2314 patients) and the Russian Federation (6 studies with 582 patients). In general, in the world, according to 51 studies analyzed, the incidence of depressive disorders in schizophrenia in men is higher than in women, although gender differences did not reach statistical significance in all regions of the world.
first_indexed 2024-03-12T02:58:26Z
format Article
id doaj.art-bcd9cc508aea4b5586c410b5eeb77f7c
institution Directory Open Access Journal
issn 2313-7053
2713-055X
language Russian
last_indexed 2025-03-14T12:37:01Z
publishDate 2021-10-01
publisher Federal State Budget Scientific Institution National Medical Research Center for Psychiatry and Neurology n.a. V.M. Bekhterev Ministry of Health of the Russian Federation
record_format Article
series Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева
spelling doaj.art-bcd9cc508aea4b5586c410b5eeb77f7c2025-03-02T09:12:46ZrusFederal State Budget Scientific Institution National Medical Research Center for Psychiatry and Neurology n.a. V.M. Bekhterev Ministry of Health of the Russian FederationОбозрение психиатрии и медицинской психологии имени В.М. Бехтерева2313-70532713-055X2021-10-01553456110.31363/2313-7053-2021-56-3-45-61408The incidence of depressive disorders in patients with schizophreniaM. A. Novitskiy0N. A. Shnayder1R. F. Nasyrova2V.M. Bekhterev National Medical Research Centre for Psychiatry and NeurologyV.M. Bekhterev National Medical Research Centre for Psychiatry and Neurology; V.F. Voino-Yasenetsky Krasnoyarsk State Medica UniversityV.M. Bekhterev National Medical Research Centre for Psychiatry and NeurologySummary. Introduction. Historically, depressive disorders have been described in various forms of schizophrenia by Kraepelin (1923) or as a reaction to illness by Bleuler (1922). One of the alternative points of view that has been considered in recent years is that depressive disorders are a comorbid condition of schizophrenia or one of the manifestations of schizophrenia. However, to date, depression, as a symptom, is not included in the diagnostic criteria of the ICD-10. Methodological approaches to diagnosing depressive disorders in patients with schizophrenia differ in different countries and research groups. This influences the prevalence rates of depressive disorders in schizophrenic patients. Purpose. The study and systematization of studies of the incidence of depressive disorders in patients with schizophrenia.Methods. Russian-language and foreign literature was analyzed with a search depth of 10 years (2010–2020) in the following databases: PubMed, Springer, Wiley Online Library, Taylor & Francis Online, US National Library of Medicine National Institutes of Health, Science Direct and eLIBRARY .RU.Results. A total of 51 studies of depressive disorders in children and adults with schizophrenia were found.Conclusion. The frequency of occurrence of depressive disorders in patients with schizophrenia varies from 9.1 and to 100%, the average frequency is 41.6%. Their frequency is variable and depends on the region of residence and ethnicity. It is noted that depressive disorders in patients with schizophrenia are more often recorded among residents of the Middle East (72.7%), Russia (61.8%) and Europe (39.6%), less often among residents of Southeast Asia (32%) and the Pacific region ( 37.3%). The countries with the highest incidence of depressive disorders in schizophrenia include: USA, Germany, China; and to the countries with the lowest frequency — Denmark, Israel, South Africa. Also, I would like to note that the largest number of studies conducted was in Europe (16 studies with 36 928 patients with schizophrenia), the USA (6 studies with 2314 patients) and the Russian Federation (6 studies with 582 patients). In general, in the world, according to 51 studies analyzed, the incidence of depressive disorders in schizophrenia in men is higher than in women, although gender differences did not reach statistical significance in all regions of the world.https://www.bekhterevreview.com/jour/article/view/584depressionschizophreniaprevalencefrequency
spellingShingle M. A. Novitskiy
N. A. Shnayder
R. F. Nasyrova
The incidence of depressive disorders in patients with schizophrenia
Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева
depression
schizophrenia
prevalence
frequency
title The incidence of depressive disorders in patients with schizophrenia
title_full The incidence of depressive disorders in patients with schizophrenia
title_fullStr The incidence of depressive disorders in patients with schizophrenia
title_full_unstemmed The incidence of depressive disorders in patients with schizophrenia
title_short The incidence of depressive disorders in patients with schizophrenia
title_sort incidence of depressive disorders in patients with schizophrenia
topic depression
schizophrenia
prevalence
frequency
url https://www.bekhterevreview.com/jour/article/view/584
work_keys_str_mv AT manovitskiy theincidenceofdepressivedisordersinpatientswithschizophrenia
AT nashnayder theincidenceofdepressivedisordersinpatientswithschizophrenia
AT rfnasyrova theincidenceofdepressivedisordersinpatientswithschizophrenia
AT manovitskiy incidenceofdepressivedisordersinpatientswithschizophrenia
AT nashnayder incidenceofdepressivedisordersinpatientswithschizophrenia
AT rfnasyrova incidenceofdepressivedisordersinpatientswithschizophrenia