Inhibition of the SLC35B2–TPST2 Axis of Tyrosine Sulfation Attenuates the Growth and Metastasis of Pancreatic Ductal AdenocarcinomSummary

Inhibition of the SLC35B2–TPST2 Axis of Tyrosine Sulfation Attenuates the Growth and Metastasis of Pancreatic Ductal AdenocarcinomSummary

Background & Aims: Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer deaths in the United States. Tyrosine sulfation, catalyzed by the tyrosylprotein sulfotransferase 2 (TPST2), is a post-translational modification essential for protein–protein interactions and ce...

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Bibliographic Details
Main Authors: Xinran Cai, Sihan Li, Xuemei Zeng, Meishu Xu, Zehua Wang, Aatur D. Singhi, Daolin Tang, Song Li, Nathan A. Yates, Da Yang, Wen Xie
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
Pancreatic Cancer
Tyrosine Sulfation
SLC35B2
TPST2
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X23000668

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