mRNA and miRNA profiling of Zika virus-infected human umbilical cord mesenchymal stem cells identifies miR-142-5p as an antiviral factor

mRNA and miRNA profiling of Zika virus-infected human umbilical cord mesenchymal stem cells identifies miR-142-5p as an antiviral factor

ABSTRACTZika virus (ZIKV) infection during pregnancy is associated with congenital brain abnormalities, a finding that highlights the urgent need to understand mother-to-fetus transmission mechanisms. Human umbilical cord mesenchymal stem cells (hUCMSCs) are susceptible to ZIKV infection but the und...

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Bibliographic Details
Main Authors: Rak-Kyun Seong, Jae Kyung Lee, Geum Joon Cho, Mukesh Kumar, Ok Sarah Shin
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Emerging Microbes and Infections
Subjects:
ZIKV
hUCMSCs
miRNA
innate immunity
RNA-seq
small RNA-seq
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2020.1821581

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https://www.tandfonline.com/doi/10.1080/22221751.2020.1821581

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