Comparative Analysis of Differentially Mutated Genes in Non-Muscle and Muscle-Invasive Bladder Cancer in the Chinese Population by Whole Exome Sequencing

Comparative Analysis of Differentially Mutated Genes in Non-Muscle and Muscle-Invasive Bladder Cancer in the Chinese Population by Whole Exome Sequencing

Objective: To characterize the spectra of mutations in non-muscle invasive bladder cancer (NMIBC) and muscle-invasive bladder cancer (MIBC) in the Chinese population to identify any mutational features and find potential therapeutic targets.Materials and methods: We collected fresh bladder tumor sam...

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Bibliographic Details
Main Authors: Fangming Wang, Xiying Dong, Feiya Yang, Nianzeng Xing
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Genetics
Subjects:
mutated gene
muscle invasive bladder cancer
non-muscle invasive bladder cancer
whole exome sequencing
comparative analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.831146/full

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https://www.frontiersin.org/articles/10.3389/fgene.2022.831146/full

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