Differential axonal trafficking of Neuropeptide Y-, LAMP1-, and RAB7-tagged organelles in vivo

Differential axonal trafficking of Neuropeptide Y-, LAMP1-, and RAB7-tagged organelles in vivo

Different organelles traveling through neurons exhibit distinct properties in vitro, but this has not been investigated in the intact mammalian brain. We established simultaneous dual color two-photon microscopy to visualize the trafficking of Neuropeptide Y (NPY)-, LAMP1-, and RAB7-tagged organelle...

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Bibliographic Details
Main Authors: Joris P Nassal, Fiona H Murphy, Ruud F Toonen, Matthijs Verhage
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-12-01
Series:eLife
Subjects:
organelle trafficking
dense core vesicles
in vivo imaging
neuropeptides
Online Access:https://elifesciences.org/articles/81721

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