Coronary artery disease risk assessment of liver transplant candidates
Cardiovascular complications are a major cause of morbidity and mortality in patients with end-stage liver disease undergoing liver transplantation (LT). Coronary artery disease (CAD) contributes to major portion of cardiovascular complications and therefore warrants evaluation in the preoperative p...
| Main Authors: | , |
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| Format: | Article |
| Language: | Bulgarian |
| Published: |
Pensoft Publishers
2020-10-01
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| Series: | Българска кардиология |
| Subjects: | |
| Online Access: | https://journal.bgcardio.org/article/54743/download/pdf/ |
| _version_ | 1797427517338943488 |
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| author | Liliya Demirevska Ivaylo Daskalov |
| author_facet | Liliya Demirevska Ivaylo Daskalov |
| author_sort | Liliya Demirevska |
| collection | DOAJ |
| description | Cardiovascular complications are a major cause of morbidity and mortality in patients with end-stage liver disease undergoing liver transplantation (LT). Coronary artery disease (CAD) contributes to major portion of cardiovascular complications and therefore warrants evaluation in the preoperative period. Patients awaiting LT are a special subgroup that carries heterogeneous risk factors and has unique pathogenic and clinical characteristics. These patients usually demonstrate increased cardiac output and a compromised response to stress. Low systemic vascular resistance and bradycardia are also commonly seen in cirrhosis and can be aggravated by beta-blocker use. Current non-invasive tests that assess for subclinical CAD have low sensitivity, and altered hemodynamics during the LT surgery can unmask latent cardiovascular disease either intraoperatively or in the immediate postoperative period. This review focuses on the expanding body of evidence for diagnosis and risk stratifi cation of CAD in LT candidates. The systematic approach to evaluate preoperative CAD risk in LT candidates may be helpful to optimize post-LT outcome. |
| first_indexed | 2024-03-09T08:46:08Z |
| format | Article |
| id | doaj.art-bce8e0bbcd0b4fd7858edc6eb43bd139 |
| institution | Directory Open Access Journal |
| issn | 2683-1015 |
| language | Bulgarian |
| last_indexed | 2024-03-09T08:46:08Z |
| publishDate | 2020-10-01 |
| publisher | Pensoft Publishers |
| record_format | Article |
| series | Българска кардиология |
| spelling | doaj.art-bce8e0bbcd0b4fd7858edc6eb43bd1392023-12-02T15:31:24ZbulPensoft PublishersБългарска кардиология2683-10152020-10-0126371610.3897/bgcardio.26.e5474354743Coronary artery disease risk assessment of liver transplant candidatesLiliya Demirevska0Ivaylo Daskalov1Military Medical AcademyMedical Military AcademiCardiovascular complications are a major cause of morbidity and mortality in patients with end-stage liver disease undergoing liver transplantation (LT). Coronary artery disease (CAD) contributes to major portion of cardiovascular complications and therefore warrants evaluation in the preoperative period. Patients awaiting LT are a special subgroup that carries heterogeneous risk factors and has unique pathogenic and clinical characteristics. These patients usually demonstrate increased cardiac output and a compromised response to stress. Low systemic vascular resistance and bradycardia are also commonly seen in cirrhosis and can be aggravated by beta-blocker use. Current non-invasive tests that assess for subclinical CAD have low sensitivity, and altered hemodynamics during the LT surgery can unmask latent cardiovascular disease either intraoperatively or in the immediate postoperative period. This review focuses on the expanding body of evidence for diagnosis and risk stratifi cation of CAD in LT candidates. The systematic approach to evaluate preoperative CAD risk in LT candidates may be helpful to optimize post-LT outcome.https://journal.bgcardio.org/article/54743/download/pdf/coronary artery diseaseliver transplantationri |
| spellingShingle | Liliya Demirevska Ivaylo Daskalov Coronary artery disease risk assessment of liver transplant candidates Българска кардиология coronary artery disease liver transplantation ri |
| title | Coronary artery disease risk assessment of liver transplant candidates |
| title_full | Coronary artery disease risk assessment of liver transplant candidates |
| title_fullStr | Coronary artery disease risk assessment of liver transplant candidates |
| title_full_unstemmed | Coronary artery disease risk assessment of liver transplant candidates |
| title_short | Coronary artery disease risk assessment of liver transplant candidates |
| title_sort | coronary artery disease risk assessment of liver transplant candidates |
| topic | coronary artery disease liver transplantation ri |
| url | https://journal.bgcardio.org/article/54743/download/pdf/ |
| work_keys_str_mv | AT liliyademirevska coronaryarterydiseaseriskassessmentoflivertransplantcandidates AT ivaylodaskalov coronaryarterydiseaseriskassessmentoflivertransplantcandidates |