The Nitric Oxide (NO) Donor Molsidomine Counteract Social Withdrawal and Cognition Deficits Induced by Blockade of the NMDA Receptor in the Rat

The Nitric Oxide (NO) Donor Molsidomine Counteract Social Withdrawal and Cognition Deficits Induced by Blockade of the NMDA Receptor in the Rat

The deficiency of the gaseous molecule nitric oxide (NO) seems to be critically involved in the pathogenesis of schizophrenia. Thus, molecules that can normalize NO levels, as are NO donors, might be of utility for the medication of this psychiatric disease. The aim of the present study was to detec...

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Bibliographic Details
Main Authors: Lamprini Katsanou, Evangelia Fragkiadaki, Sotirios Kampouris, Anastasia Konstanta, Aikaterini Vontzou, Nikolaos Pitsikas
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
nitric oxide
molsidomine
clozapine
ketamine
schizophrenia
rat
Online Access:https://www.mdpi.com/1422-0067/24/7/6866

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