Mathematical Modeling and backward bifurcation in monkeypox disease under real observed data

We propose a mathematical model to analyze the monkeypox disease in the context of the known cases of the USA epidemic. We formulate the model and obtain their essential properties. The equilibrium points are found and their stability is demonstrated. We prove that the model is locally asymptotical...

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Main Authors: F.M. Allehiany, Mahmoud H. DarAssi, Irfan Ahmad, Muhammad Altaf Khan, Elsayed M. Tag-eldin
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Results in Physics
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211379723003509
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author F.M. Allehiany
Mahmoud H. DarAssi
Irfan Ahmad
Muhammad Altaf Khan
Elsayed M. Tag-eldin
author_facet F.M. Allehiany
Mahmoud H. DarAssi
Irfan Ahmad
Muhammad Altaf Khan
Elsayed M. Tag-eldin
author_sort F.M. Allehiany
collection DOAJ
description We propose a mathematical model to analyze the monkeypox disease in the context of the known cases of the USA epidemic. We formulate the model and obtain their essential properties. The equilibrium points are found and their stability is demonstrated. We prove that the model is locally asymptotical stable (LAS) at disease free equilibrium (DFE) under R0<1. The presence of an endemic equilibrium is demonstrated, and the phenomena of backward bifurcation is discovered in the monkeypox disease model. In the monkeypox infectious disease model, the parameters that lead to backward bifurcation are θr, τ1, and ξr. When R0>1, we determine the model’s global asymptotical stability (GAS). To parameterize the model using real data, we obtain the real value of the model parameters and compute R1=0.5905. Additionally, we do a sensitivity analysis on the parameters in R0. We conclude by presenting specific numerical findings.
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spelling doaj.art-bcec2d633b88407092d2cdcc8d6f2d522023-06-17T05:18:09ZengElsevierResults in Physics2211-37972023-07-0150106557Mathematical Modeling and backward bifurcation in monkeypox disease under real observed dataF.M. Allehiany0Mahmoud H. DarAssi1Irfan Ahmad2Muhammad Altaf Khan3Elsayed M. Tag-eldin4Department of Mathematical Sciences, College of Applied Sciences, Umm Al-Qura University, Saudi ArabiaDepartment of Basic Sciences, Princess Sumaya University for Technology, Amman 11941, JordanDepartment of Clinical Laboratory Sciences, College of Applied Medical Science, King Khalid University, Abha 61421, Saudi ArabiaFaculty of Natural and Agricultural Sciences, University of the Free State, South Africa; Corresponding author.Faculty of Engineering, Future University in Egypt, New Cairo 11835, EgyptWe propose a mathematical model to analyze the monkeypox disease in the context of the known cases of the USA epidemic. We formulate the model and obtain their essential properties. The equilibrium points are found and their stability is demonstrated. We prove that the model is locally asymptotical stable (LAS) at disease free equilibrium (DFE) under R0<1. The presence of an endemic equilibrium is demonstrated, and the phenomena of backward bifurcation is discovered in the monkeypox disease model. In the monkeypox infectious disease model, the parameters that lead to backward bifurcation are θr, τ1, and ξr. When R0>1, we determine the model’s global asymptotical stability (GAS). To parameterize the model using real data, we obtain the real value of the model parameters and compute R1=0.5905. Additionally, we do a sensitivity analysis on the parameters in R0. We conclude by presenting specific numerical findings.http://www.sciencedirect.com/science/article/pii/S2211379723003509Mathematical modelMonkeypox diseaseOutbreak dataEquilibrium pointsGlobal stabilityNumerical results
spellingShingle F.M. Allehiany
Mahmoud H. DarAssi
Irfan Ahmad
Muhammad Altaf Khan
Elsayed M. Tag-eldin
Mathematical Modeling and backward bifurcation in monkeypox disease under real observed data
Results in Physics
Mathematical model
Monkeypox disease
Outbreak data
Equilibrium points
Global stability
Numerical results
title Mathematical Modeling and backward bifurcation in monkeypox disease under real observed data
title_full Mathematical Modeling and backward bifurcation in monkeypox disease under real observed data
title_fullStr Mathematical Modeling and backward bifurcation in monkeypox disease under real observed data
title_full_unstemmed Mathematical Modeling and backward bifurcation in monkeypox disease under real observed data
title_short Mathematical Modeling and backward bifurcation in monkeypox disease under real observed data
title_sort mathematical modeling and backward bifurcation in monkeypox disease under real observed data
topic Mathematical model
Monkeypox disease
Outbreak data
Equilibrium points
Global stability
Numerical results
url http://www.sciencedirect.com/science/article/pii/S2211379723003509
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