SPC Liposomes as Possible Delivery Systems for Improving Bioavailability of the Natural Sesquiterpene β-Caryophyllene: Lamellarity and Drug-Loading as Key Features for a Rational Drug Delivery Design

SPC Liposomes as Possible Delivery Systems for Improving Bioavailability of the Natural Sesquiterpene β-Caryophyllene: Lamellarity and Drug-Loading as Key Features for a Rational Drug Delivery Design

The natural sesquiterpene β-caryophyllene (CRY) has been highlighted to possess interesting pharmacological potentials, particularly due to its chemopreventive and analgesic properties. However, the poor solubility of this sesquiterpene in aqueous fluids can hinder its uptake into cells, re...

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Bibliographic Details
Main Authors: Antonella Di Sotto, Patrizia Paolicelli, Martina Nardoni, Lorena Abete, Stefania Garzoli, Silvia Di Giacomo, Gabriela Mazzanti, Maria Antonietta Casadei, Stefania Petralito
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Pharmaceutics
Subjects:
lipophilic compound
caryophyllene sesquiterpene
antiproliferative activity
liposomes
lamellarity
drug loading
Online Access:https://www.mdpi.com/1999-4923/10/4/274

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