Asymmetric cell division safeguards memory CD8 T cell development

Asymmetric cell division safeguards memory CD8 T cell development

Summary: The strength of T cell receptor (TCR) stimulation and asymmetric distribution of fate determinants are both implied to affect T cell differentiation. Here, we uncover asymmetric cell division (ACD) as a safeguard mechanism for memory CD8 T cell generation specifically upon strong TCR stimul...

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Bibliographic Details
Main Authors: Fabienne Gräbnitz, Dominique Stark, Danielle Shlesinger, Anthony Petkidis, Mariana Borsa, Alexander Yermanos, Andreas Carr, Niculò Barandun, Arne Wehling, Miroslav Balaz, Timm Schroeder, Annette Oxenius
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Cell Reports
Subjects:
CP: Immunology
CP: Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723004795

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