Next-generation sequencing: insights to advance clinical investigations of the microbiome
Next-generation sequencing (NGS) technology has advanced our understanding of the human microbiome by allowing for the discovery and characterization of unculturable microbes with prediction of their function. Key NGS methods include 16S rRNA gene sequencing, shotgun metagenomic sequencing, and RNA...
Main Authors: | Caroline R. Wensel, Jennifer L. Pluznick, Steven L. Salzberg, Cynthia L. Sears |
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Format: | Article |
Language: | English |
Published: |
American Society for Clinical Investigation
2022-04-01
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Series: | The Journal of Clinical Investigation |
Online Access: | https://doi.org/10.1172/JCI154944 |
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