NOX1 supports the metabolic remodeling of HepG2 cells.
NADPH oxidases are important sources of reactive oxygen species (ROS) which act as signaling molecules in the regulation of protein expression, cell proliferation, differentiation, migration and cell death. The NOX1 subunit is over-expressed in several cancers and NOX1 derived ROS have been repeated...
Main Authors: | Katharina Bertram, Cristina-Maria Valcu, Michael Weitnauer, Uwe Linne, Agnes Görlach |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4373763?pdf=render |
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