Characterization of Single-Chain Fv Fragments of Neutralizing Antibodies to Rabies Virus Glycoprotein

Characterization of Single-Chain Fv Fragments of Neutralizing Antibodies to Rabies Virus Glycoprotein

Rabies has almost a 100% case-fatality rate and kills more than 59,000 people annually around the world. There is no established treatment for rabies. The rabies virus (RABV) expresses only the glycoprotein (RABVG) at the viral surface, and it is the target for the neutralizing antibodies. We previo...

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Bibliographic Details
Main Authors: Kohei Yumoto, Tomoaki Arisaka, Kazuma Okada, Kyosuke Aoki, Toyoyuki Ose, Tatsunori Masatani, Makoto Sugiyama, Naoto Ito, Hideo Fukuhara, Katsumi Maenaka
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Viruses
Subjects:
rabies virus
rabies virus glycoprotein
single-chain Fv
Fab
neutralization antibody
biolayer interferometry (BLI)
Online Access:https://www.mdpi.com/1999-4915/13/11/2311

Internet

https://www.mdpi.com/1999-4915/13/11/2311

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