Pityriasis rubra pilaris‐like graft‐vs‐host disease following allogeneic stem cell transplant in two patients
Abstract Chronic cutaneous graft‐vs‐host disease (GVHD) has several atypical variants. We describe two cases of GVHD with clinical and histopathologic features of pityriasis rubra pilaris (PRP), which responded to additional immunosuppression. Recognition of this newly described PRP‐like clinical pr...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2019-12-01
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| Series: | Clinical Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ccr3.2458 |
| _version_ | 1818855015396147200 |
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| author | Jennifer Y. Wang Mika M. Tabata Silvina Pugliese Darci Phillips Jinah Kim Wen‐Kai Weng Bernice Y. Kwong |
| author_facet | Jennifer Y. Wang Mika M. Tabata Silvina Pugliese Darci Phillips Jinah Kim Wen‐Kai Weng Bernice Y. Kwong |
| author_sort | Jennifer Y. Wang |
| collection | DOAJ |
| description | Abstract Chronic cutaneous graft‐vs‐host disease (GVHD) has several atypical variants. We describe two cases of GVHD with clinical and histopathologic features of pityriasis rubra pilaris (PRP), which responded to additional immunosuppression. Recognition of this newly described PRP‐like clinical presentation of GVHD may prompt early consideration of additional steroid‐sparing therapies. |
| first_indexed | 2024-12-19T08:01:53Z |
| format | Article |
| id | doaj.art-bd06a904849842fb96256cef02b4fb89 |
| institution | Directory Open Access Journal |
| issn | 2050-0904 |
| language | English |
| last_indexed | 2024-12-19T08:01:53Z |
| publishDate | 2019-12-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj.art-bd06a904849842fb96256cef02b4fb892022-12-21T20:29:50ZengWileyClinical Case Reports2050-09042019-12-017122491249410.1002/ccr3.2458Pityriasis rubra pilaris‐like graft‐vs‐host disease following allogeneic stem cell transplant in two patientsJennifer Y. Wang0Mika M. Tabata1Silvina Pugliese2Darci Phillips3Jinah Kim4Wen‐Kai Weng5Bernice Y. Kwong6Department of Dermatology Stanford University Medical Center Stanford CaliforniaDepartment of Dermatology Stanford University Medical Center Stanford CaliforniaDepartment of Dermatology Stanford University Medical Center Stanford CaliforniaDepartment of Dermatology Stanford University Medical Center Stanford CaliforniaDepartment of Dermatology Stanford University Medical Center Stanford CaliforniaDivision of Blood and Marrow Transplantation Department of Medicine Stanford University Medical Center Stanford CaliforniaDepartment of Dermatology Stanford University Medical Center Stanford CaliforniaAbstract Chronic cutaneous graft‐vs‐host disease (GVHD) has several atypical variants. We describe two cases of GVHD with clinical and histopathologic features of pityriasis rubra pilaris (PRP), which responded to additional immunosuppression. Recognition of this newly described PRP‐like clinical presentation of GVHD may prompt early consideration of additional steroid‐sparing therapies.https://doi.org/10.1002/ccr3.2458allogeneic hematopoietic cell transplantationcutaneous graft‐vs‐host diseaseimmunosuppressionpityriasis rubra pilaris |
| spellingShingle | Jennifer Y. Wang Mika M. Tabata Silvina Pugliese Darci Phillips Jinah Kim Wen‐Kai Weng Bernice Y. Kwong Pityriasis rubra pilaris‐like graft‐vs‐host disease following allogeneic stem cell transplant in two patients Clinical Case Reports allogeneic hematopoietic cell transplantation cutaneous graft‐vs‐host disease immunosuppression pityriasis rubra pilaris |
| title | Pityriasis rubra pilaris‐like graft‐vs‐host disease following allogeneic stem cell transplant in two patients |
| title_full | Pityriasis rubra pilaris‐like graft‐vs‐host disease following allogeneic stem cell transplant in two patients |
| title_fullStr | Pityriasis rubra pilaris‐like graft‐vs‐host disease following allogeneic stem cell transplant in two patients |
| title_full_unstemmed | Pityriasis rubra pilaris‐like graft‐vs‐host disease following allogeneic stem cell transplant in two patients |
| title_short | Pityriasis rubra pilaris‐like graft‐vs‐host disease following allogeneic stem cell transplant in two patients |
| title_sort | pityriasis rubra pilaris like graft vs host disease following allogeneic stem cell transplant in two patients |
| topic | allogeneic hematopoietic cell transplantation cutaneous graft‐vs‐host disease immunosuppression pityriasis rubra pilaris |
| url | https://doi.org/10.1002/ccr3.2458 |
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