The contentious relationship between artificial sweeteners and cardiovascular health

Abstract Sweet has always been a fundamental human taste, and while glucose and other kinds of sugar are our primary energy sources, they can also have detrimental effects on health, including weight gain, obesity, cardiovascular diseases, diabetes, and other metabolic diseases. Artificial sweetener...

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Main Authors: Sandeep Singh, Aditya Kohli, Stuti Trivedi, Sai Gautham Kanagala, F. N. U. Anamika, Nikita Garg, Meet A. Patel, Ripudaman Singh Munjal, Rohit Jain
Format: Article
Language:English
Published: SpringerOpen 2023-06-01
Series:The Egyptian Journal of Internal Medicine
Subjects:
Online Access:https://doi.org/10.1186/s43162-023-00232-1
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author Sandeep Singh
Aditya Kohli
Stuti Trivedi
Sai Gautham Kanagala
F. N. U. Anamika
Nikita Garg
Meet A. Patel
Ripudaman Singh Munjal
Rohit Jain
author_facet Sandeep Singh
Aditya Kohli
Stuti Trivedi
Sai Gautham Kanagala
F. N. U. Anamika
Nikita Garg
Meet A. Patel
Ripudaman Singh Munjal
Rohit Jain
author_sort Sandeep Singh
collection DOAJ
description Abstract Sweet has always been a fundamental human taste, and while glucose and other kinds of sugar are our primary energy sources, they can also have detrimental effects on health, including weight gain, obesity, cardiovascular diseases, diabetes, and other metabolic diseases. Artificial sweeteners (AS), introduced as sugar substitutes, are a group of chemical compounds that attribute sweetness with almost zero calories and are considered safe for consumption by the Food and Drug Administration (FDA). Although they may help restrict the daily caloric intake of sugar to less than 10% of the daily caloric intake, there are still questions about the long-term safety of AS. A higher risk of hypertension, insulin resistance, high blood sugar, abdominal obesity, and dyslipidemia has been linked to AS. The effect of AS on the cardiovascular system is still unclear, and further research is required. This review examines the potential mechanism of how artificial sweeteners cause cardiovascular diseases.
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spelling doaj.art-bd07891f98114ed8a4c17322ade5d64f2023-06-25T11:29:44ZengSpringerOpenThe Egyptian Journal of Internal Medicine2090-90982023-06-013511610.1186/s43162-023-00232-1The contentious relationship between artificial sweeteners and cardiovascular healthSandeep Singh0Aditya Kohli1Stuti Trivedi2Sai Gautham Kanagala3F. N. U. Anamika4Nikita Garg5Meet A. Patel6Ripudaman Singh Munjal7Rohit Jain8Indiana University School of MedicineDayanand Medical College and HospitalGovernment Medical CollegeOsmania Medical CollegeUniversity College of Medical SciencesSouthern Illinois University School of MedicineTianjin Medical UniversityTouro University College of Osteopathic MedicinePenn State Health Milton S. Hershey Medical CenterAbstract Sweet has always been a fundamental human taste, and while glucose and other kinds of sugar are our primary energy sources, they can also have detrimental effects on health, including weight gain, obesity, cardiovascular diseases, diabetes, and other metabolic diseases. Artificial sweeteners (AS), introduced as sugar substitutes, are a group of chemical compounds that attribute sweetness with almost zero calories and are considered safe for consumption by the Food and Drug Administration (FDA). Although they may help restrict the daily caloric intake of sugar to less than 10% of the daily caloric intake, there are still questions about the long-term safety of AS. A higher risk of hypertension, insulin resistance, high blood sugar, abdominal obesity, and dyslipidemia has been linked to AS. The effect of AS on the cardiovascular system is still unclear, and further research is required. This review examines the potential mechanism of how artificial sweeteners cause cardiovascular diseases.https://doi.org/10.1186/s43162-023-00232-1Artificial sweetenersCardiovascular healthAtrial fibrillationAspartameSaccharin
spellingShingle Sandeep Singh
Aditya Kohli
Stuti Trivedi
Sai Gautham Kanagala
F. N. U. Anamika
Nikita Garg
Meet A. Patel
Ripudaman Singh Munjal
Rohit Jain
The contentious relationship between artificial sweeteners and cardiovascular health
The Egyptian Journal of Internal Medicine
Artificial sweeteners
Cardiovascular health
Atrial fibrillation
Aspartame
Saccharin
title The contentious relationship between artificial sweeteners and cardiovascular health
title_full The contentious relationship between artificial sweeteners and cardiovascular health
title_fullStr The contentious relationship between artificial sweeteners and cardiovascular health
title_full_unstemmed The contentious relationship between artificial sweeteners and cardiovascular health
title_short The contentious relationship between artificial sweeteners and cardiovascular health
title_sort contentious relationship between artificial sweeteners and cardiovascular health
topic Artificial sweeteners
Cardiovascular health
Atrial fibrillation
Aspartame
Saccharin
url https://doi.org/10.1186/s43162-023-00232-1
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