Comparison of quality of life in patients undergoing transhiatal esophagectomy with or without chemotherapy
Background/Aim: To compare the quality of life (QOL) in patients undergoing transhiatal esophagectomy (THE) with or without chemotherapy, who were admitted to the Post Graduate Institute of Medical Education and Research, Chandigarh and enrolled in the study, from July 2004 to October 2005. Patients...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2012-01-01
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| Series: | The Saudi Journal of Gastroenterology |
| Subjects: | |
| Online Access: | http://www.saudijgastro.com/article.asp?issn=1319-3767;year=2012;volume=18;issue=3;spage=195;epage=200;aulast=Kataria |
| _version_ | 1818217315669377024 |
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| author | Kamal Kataria Ganga R Verma Anil Malhotra Rajni Yadav |
| author_facet | Kamal Kataria Ganga R Verma Anil Malhotra Rajni Yadav |
| author_sort | Kamal Kataria |
| collection | DOAJ |
| description | Background/Aim: To compare the quality of life (QOL) in patients undergoing transhiatal esophagectomy (THE) with or without chemotherapy, who were admitted to the Post Graduate Institute of Medical Education and Research, Chandigarh and enrolled in the study, from July 2004 to October 2005. Patients and Methods: Thirty patients of esophageal carcinoma by purposive sampling were randomized into two groups i.e., patients undergoing THE after chemotherapy and patients undergoing THE without chemotherapy. Two QOL questionnaires, one generic i.e., EORTC-QLQ C-30 (European Organization for Research and Treatment of Cancer) and other esophageal cancer-specific i.e., EORTC OES-18 were utilized to assess the QOL. Result: Physical functional scales were better in patients, who received neoadjuvant chemotherapy. The role and social aspects of functional scales deteriorated after completion of treatment in both groups. This was primarily due to the effect of surgery. However, they were better from an emotional and cognitive point of value after surgery and radiotherapy. Fourteen out of 30 patients experienced vomiting and diarrhea due to radiotherapy. Conclusion: THE in esophageal carcinoma improves global health scales and majority of symptom scales in all patients. QOL improvement in general was better in patients who were administered neoadjuvant chemotherapy along with surgery. |
| first_indexed | 2024-12-12T07:05:55Z |
| format | Article |
| id | doaj.art-bd079eb5c60f426682b05cd3f1b40a05 |
| institution | Directory Open Access Journal |
| issn | 1319-3767 1998-4049 |
| language | English |
| last_indexed | 2024-12-12T07:05:55Z |
| publishDate | 2012-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | The Saudi Journal of Gastroenterology |
| spelling | doaj.art-bd079eb5c60f426682b05cd3f1b40a052022-12-22T00:33:44ZengWolters Kluwer Medknow PublicationsThe Saudi Journal of Gastroenterology1319-37671998-40492012-01-0118319520010.4103/1319-3767.96454Comparison of quality of life in patients undergoing transhiatal esophagectomy with or without chemotherapyKamal KatariaGanga R VermaAnil MalhotraRajni YadavBackground/Aim: To compare the quality of life (QOL) in patients undergoing transhiatal esophagectomy (THE) with or without chemotherapy, who were admitted to the Post Graduate Institute of Medical Education and Research, Chandigarh and enrolled in the study, from July 2004 to October 2005. Patients and Methods: Thirty patients of esophageal carcinoma by purposive sampling were randomized into two groups i.e., patients undergoing THE after chemotherapy and patients undergoing THE without chemotherapy. Two QOL questionnaires, one generic i.e., EORTC-QLQ C-30 (European Organization for Research and Treatment of Cancer) and other esophageal cancer-specific i.e., EORTC OES-18 were utilized to assess the QOL. Result: Physical functional scales were better in patients, who received neoadjuvant chemotherapy. The role and social aspects of functional scales deteriorated after completion of treatment in both groups. This was primarily due to the effect of surgery. However, they were better from an emotional and cognitive point of value after surgery and radiotherapy. Fourteen out of 30 patients experienced vomiting and diarrhea due to radiotherapy. Conclusion: THE in esophageal carcinoma improves global health scales and majority of symptom scales in all patients. QOL improvement in general was better in patients who were administered neoadjuvant chemotherapy along with surgery.http://www.saudijgastro.com/article.asp?issn=1319-3767;year=2012;volume=18;issue=3;spage=195;epage=200;aulast=KatariaEsophagectomyfunctional scaleglobal health scaleneoadjuvantquality of lifetranshiatal |
| spellingShingle | Kamal Kataria Ganga R Verma Anil Malhotra Rajni Yadav Comparison of quality of life in patients undergoing transhiatal esophagectomy with or without chemotherapy The Saudi Journal of Gastroenterology Esophagectomy functional scale global health scale neoadjuvant quality of life transhiatal |
| title | Comparison of quality of life in patients undergoing transhiatal esophagectomy with or without chemotherapy |
| title_full | Comparison of quality of life in patients undergoing transhiatal esophagectomy with or without chemotherapy |
| title_fullStr | Comparison of quality of life in patients undergoing transhiatal esophagectomy with or without chemotherapy |
| title_full_unstemmed | Comparison of quality of life in patients undergoing transhiatal esophagectomy with or without chemotherapy |
| title_short | Comparison of quality of life in patients undergoing transhiatal esophagectomy with or without chemotherapy |
| title_sort | comparison of quality of life in patients undergoing transhiatal esophagectomy with or without chemotherapy |
| topic | Esophagectomy functional scale global health scale neoadjuvant quality of life transhiatal |
| url | http://www.saudijgastro.com/article.asp?issn=1319-3767;year=2012;volume=18;issue=3;spage=195;epage=200;aulast=Kataria |
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