Retroviruses hijack chromatin loops to drive oncogene expression and highlight the chromatin architecture around proto-oncogenic loci.

The majority of the genome consists of intergenic and non-coding DNA sequences shown to play a major role in different gene regulatory networks. However, the specific potency of these distal elements as well as how these regions exert function across large genomic distances remains unclear. To addre...

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Hlavní autoři: Jillian M Pattison, Jason B Wright, Michael D Cole
Médium: Článek
Jazyk:English
Vydáno: Public Library of Science (PLoS) 2015-01-01
Edice:PLoS ONE
On-line přístup:http://europepmc.org/articles/PMC4370588?pdf=render