Orthohantavirus Isolated in Reservoir Host Cells Displays Minimal Genetic Changes and Retains Wild-Type Infection Properties

Orthohantavirus Isolated in Reservoir Host Cells Displays Minimal Genetic Changes and Retains Wild-Type Infection Properties

Orthohantaviruses are globally emerging zoonotic pathogens. While the reservoir host role of several rodent species is well-established, detailed research on the mechanisms of host-othohantavirus interactions has been constrained by the lack of an experimental system that is able to effectively repl...

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Bibliographic Details
Main Authors: Tomas Strandin, Teemu Smura, Paula Ahola, Kirsi Aaltonen, Tarja Sironen, Jussi Hepojoki, Isabella Eckerle, Rainer G. Ulrich, Olli Vapalahti, Anja Kipar, Kristian M. Forbes
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Viruses
Subjects:
immunity
Puumala orthohantavirus
rodent reservoir
spillover
vole
zoonoses
Online Access:https://www.mdpi.com/1999-4915/12/4/457

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