Gut Microbiome Composition Linked to Inflammatory Factors and Cognitive Functions in First-Episode, Drug-Naive Major Depressive Disorder Patients

Gut Microbiome Composition Linked to Inflammatory Factors and Cognitive Functions in First-Episode, Drug-Naive Major Depressive Disorder Patients

ObjectiveThe microbiota–gut–brain axis, especially the inflammatory pathway, may play a critical role in the pathogenesis of cognitive impairment in major depressive disorder (MDD). However, studies on the microbiota-inflammatory-cognitive function axis in MDD are lacking. The aim of the present stu...

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Bibliographic Details
Main Authors: Penghong Liu, Mingxue Gao, Zhifen Liu, Yanyan Zhang, Hongwei Tu, Lei Lei, Peiyi Wu, Aixia Zhang, Chunxia Yang, Gaizhi Li, Ning Sun, Kerang Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Neuroscience
Subjects:
major depressive disorder
gut microbiome
diversity
inflammatory factors
cognitive function
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.800764/full

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