Integrative GWAS and co-localisation analysis suggests novel genes associated with age-related multimorbidity

Abstract Advancing age is the greatest risk factor for developing multiple age-related diseases. Therapeutic approaches targeting the underlying pathways of ageing, rather than individual diseases, may be an effective way to treat and prevent age-related morbidity while reducing the burden of polyph...

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Bibliographic Details
Main Authors: Clare E. West, Mohd Karim, Maria J. Falaguera, Leo Speidel, Charlotte J. Green, Lisa Logie, Jeremy Schwartzentruber, David Ochoa, Janet M. Lord, Michael A. J. Ferguson, Chas Bountra, Graeme F. Wilkinson, Beverley Vaughan, Andrew R. Leach, Ian Dunham, Brian D. Marsden
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Scientific Data
Online Access:https://doi.org/10.1038/s41597-023-02513-4