Hendra Virus Vaccine, a One Health Approach to Protecting Horse, Human, and Environmental Health

In recent years, the emergence of several highly pathogenic zoonotic diseases in humans has led to a renewed emphasis on the interconnectedness of human, animal, and environmental health, otherwise known as One Health. For example, Hendra virus (HeV), a zoonotic paramyxovirus, was discovered in 1994...

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Main Authors: Deborah Middleton, Jackie Pallister, Reuben Klein, Yan-Ru Feng, Jessica Haining, Rachel Arkinstall, Leah Frazer, Jin-An Huang, Nigel Edwards, Mark Wareing, Martin Elhay, Zia Hashmi, John Bingham, Manabu Yamada, Dayna Johnson, John White, Adam Foord, Hans G. Heine, Glenn A. Marsh, Christopher C. Broder, Lin-Fa Wang
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2014-03-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/20/3/13-1159_article
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author Deborah Middleton
Jackie Pallister
Reuben Klein
Yan-Ru Feng
Jessica Haining
Rachel Arkinstall
Leah Frazer
Jin-An Huang
Nigel Edwards
Mark Wareing
Martin Elhay
Zia Hashmi
John Bingham
Manabu Yamada
Dayna Johnson
John White
Adam Foord
Hans G. Heine
Glenn A. Marsh
Christopher C. Broder
Lin-Fa Wang
author_facet Deborah Middleton
Jackie Pallister
Reuben Klein
Yan-Ru Feng
Jessica Haining
Rachel Arkinstall
Leah Frazer
Jin-An Huang
Nigel Edwards
Mark Wareing
Martin Elhay
Zia Hashmi
John Bingham
Manabu Yamada
Dayna Johnson
John White
Adam Foord
Hans G. Heine
Glenn A. Marsh
Christopher C. Broder
Lin-Fa Wang
author_sort Deborah Middleton
collection DOAJ
description In recent years, the emergence of several highly pathogenic zoonotic diseases in humans has led to a renewed emphasis on the interconnectedness of human, animal, and environmental health, otherwise known as One Health. For example, Hendra virus (HeV), a zoonotic paramyxovirus, was discovered in 1994, and since then, infections have occurred in 7 humans, each of whom had a strong epidemiologic link to similarly affected horses. As a consequence of these outbreaks, eradication of bat populations was discussed, despite their crucial environmental roles in pollination and reduction of the insect population. We describe the development and evaluation of a vaccine for horses with the potential for breaking the chain of HeV transmission from bats to horses to humans, thereby protecting horse, human, and environmental health. The HeV vaccine for horses is a key example of a One Health approach to the control of human disease. Download MP3  Length: 1:13
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spelling doaj.art-bd0ad1356e2542caa3bf5dc9b30f30432022-12-21T19:10:15ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592014-03-0120337937910.3201/eid2003.131159Hendra Virus Vaccine, a One Health Approach to Protecting Horse, Human, and Environmental HealthDeborah MiddletonJackie PallisterReuben KleinYan-Ru FengJessica HainingRachel ArkinstallLeah FrazerJin-An HuangNigel EdwardsMark WareingMartin ElhayZia HashmiJohn BinghamManabu YamadaDayna JohnsonJohn WhiteAdam FoordHans G. HeineGlenn A. MarshChristopher C. BroderLin-Fa WangIn recent years, the emergence of several highly pathogenic zoonotic diseases in humans has led to a renewed emphasis on the interconnectedness of human, animal, and environmental health, otherwise known as One Health. For example, Hendra virus (HeV), a zoonotic paramyxovirus, was discovered in 1994, and since then, infections have occurred in 7 humans, each of whom had a strong epidemiologic link to similarly affected horses. As a consequence of these outbreaks, eradication of bat populations was discussed, despite their crucial environmental roles in pollination and reduction of the insect population. We describe the development and evaluation of a vaccine for horses with the potential for breaking the chain of HeV transmission from bats to horses to humans, thereby protecting horse, human, and environmental health. The HeV vaccine for horses is a key example of a One Health approach to the control of human disease. Download MP3  Length: 1:13https://wwwnc.cdc.gov/eid/article/20/3/13-1159_articleHendra virusHeVvaccineHeV vaccineOne-HealthG glycoprotein
spellingShingle Deborah Middleton
Jackie Pallister
Reuben Klein
Yan-Ru Feng
Jessica Haining
Rachel Arkinstall
Leah Frazer
Jin-An Huang
Nigel Edwards
Mark Wareing
Martin Elhay
Zia Hashmi
John Bingham
Manabu Yamada
Dayna Johnson
John White
Adam Foord
Hans G. Heine
Glenn A. Marsh
Christopher C. Broder
Lin-Fa Wang
Hendra Virus Vaccine, a One Health Approach to Protecting Horse, Human, and Environmental Health
Emerging Infectious Diseases
Hendra virus
HeV
vaccine
HeV vaccine
One-Health
G glycoprotein
title Hendra Virus Vaccine, a One Health Approach to Protecting Horse, Human, and Environmental Health
title_full Hendra Virus Vaccine, a One Health Approach to Protecting Horse, Human, and Environmental Health
title_fullStr Hendra Virus Vaccine, a One Health Approach to Protecting Horse, Human, and Environmental Health
title_full_unstemmed Hendra Virus Vaccine, a One Health Approach to Protecting Horse, Human, and Environmental Health
title_short Hendra Virus Vaccine, a One Health Approach to Protecting Horse, Human, and Environmental Health
title_sort hendra virus vaccine a one health approach to protecting horse human and environmental health
topic Hendra virus
HeV
vaccine
HeV vaccine
One-Health
G glycoprotein
url https://wwwnc.cdc.gov/eid/article/20/3/13-1159_article
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