Metabolic effects of nettle extract in diabetes mellitus

The blood level of glucose, glycosylated hemoglobin, triglycerides, total cholesterol, summary content of very low density and low density lipoproteins, high density lipoproteins glycosylation's degree had been decreased with the nettle (Urtica dioica) extract in experimental diabetes mellitus...

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Main Authors: T. V. Yakimova, O. N. Nasanova, M. V. Meleshko, V. N. Burkova
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2011-10-01
Series:Бюллетень сибирской медицины
Subjects:
Online Access:https://bulletin.ssmu.ru/jour/article/view/1479
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author T. V. Yakimova
O. N. Nasanova
M. V. Meleshko
V. N. Burkova
author_facet T. V. Yakimova
O. N. Nasanova
M. V. Meleshko
V. N. Burkova
author_sort T. V. Yakimova
collection DOAJ
description The blood level of glucose, glycosylated hemoglobin, triglycerides, total cholesterol, summary content of very low density and low density lipoproteins, high density lipoproteins glycosylation's degree had been decreased with the nettle (Urtica dioica) extract in experimental diabetes mellitus type II in rats that was being caused with streptozotocine intraperitoneal injection and high-fat diet. The effect did not depend on food regimen during the therapy. The cholesterol atherogenic index has been decreased and the sensitivity to insulin has been recovered with the nettle extract when high-fat diet only. The level of blood glucose and glycosylated hemoglobin has been decreased with metformin when usual food regimen during the therapy. The lipid content and cholesterol atherogenic index has been normalized with metformin when both variant of diet.
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spelling doaj.art-bd0bd8784945439d998d941280e4b5a92023-03-13T09:58:15ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842011-10-0110511612010.20538/1682-0363-2011-5-116-120985Metabolic effects of nettle extract in diabetes mellitusT. V. Yakimova0O. N. Nasanova1M. V. Meleshko2V. N. Burkova3Сибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетThe blood level of glucose, glycosylated hemoglobin, triglycerides, total cholesterol, summary content of very low density and low density lipoproteins, high density lipoproteins glycosylation's degree had been decreased with the nettle (Urtica dioica) extract in experimental diabetes mellitus type II in rats that was being caused with streptozotocine intraperitoneal injection and high-fat diet. The effect did not depend on food regimen during the therapy. The cholesterol atherogenic index has been decreased and the sensitivity to insulin has been recovered with the nettle extract when high-fat diet only. The level of blood glucose and glycosylated hemoglobin has been decreased with metformin when usual food regimen during the therapy. The lipid content and cholesterol atherogenic index has been normalized with metformin when both variant of diet.https://bulletin.ssmu.ru/jour/article/view/1479модель сахарного диабета типа 2экстракт крапивыметформингипергликемиядислипидемия
spellingShingle T. V. Yakimova
O. N. Nasanova
M. V. Meleshko
V. N. Burkova
Metabolic effects of nettle extract in diabetes mellitus
Бюллетень сибирской медицины
модель сахарного диабета типа 2
экстракт крапивы
метформин
гипергликемия
дислипидемия
title Metabolic effects of nettle extract in diabetes mellitus
title_full Metabolic effects of nettle extract in diabetes mellitus
title_fullStr Metabolic effects of nettle extract in diabetes mellitus
title_full_unstemmed Metabolic effects of nettle extract in diabetes mellitus
title_short Metabolic effects of nettle extract in diabetes mellitus
title_sort metabolic effects of nettle extract in diabetes mellitus
topic модель сахарного диабета типа 2
экстракт крапивы
метформин
гипергликемия
дислипидемия
url https://bulletin.ssmu.ru/jour/article/view/1479
work_keys_str_mv AT tvyakimova metaboliceffectsofnettleextractindiabetesmellitus
AT onnasanova metaboliceffectsofnettleextractindiabetesmellitus
AT mvmeleshko metaboliceffectsofnettleextractindiabetesmellitus
AT vnburkova metaboliceffectsofnettleextractindiabetesmellitus