Effects of Low Concentrations of Rotenone Upon Mitohormesis in SH-SY5Y Cells

Effects of Low Concentrations of Rotenone Upon Mitohormesis in SH-SY5Y Cells

The mitochondrial toxin rotenone exerts cytotoxicity via overproduction of reactive oxygen species (ROS) and depolarization of the mitochondrial membrane. We investigated the effects of rotenone (12.5, 25, 50, 100 nmol/L) on mitochondrial biogenesis and the potential roles of ROS production in SH-SY...

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Bibliographic Details
Main Authors:	Xiong Yuyun, Qian Jinjun, Xu Minfang, Qiu Jing, Xia Juan, Ma Rui, Zhu Li, Gao Jing
Format:	Article
Language:	English
Published:	SAGE Publishing 2013-04-01
Series:	Dose-Response
Online Access:	https://doi.org/10.2203/dose-response.12-005.Gao

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