Deep molecular learning of transcriptional control of a synthetic CRE enhancer and its variants
Summary: Massively parallel reporter assay measures transcriptional activities of various cis-regulatory modules (CRMs) in a single experiment. We developed a thermodynamic computational model framework that calculates quantitative levels of gene expression directly from regulatory DNA sequences. Us...
Main Authors: | Chan-Koo Kang, Ah-Ram Kim |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2024-01-01
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Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004223028249 |
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