CMV infection among HIV / AIDS patients in Iraq

Background: The aim of the study was to determine the prevalence of CMV infection among HIV / AIDS patients in relation to disease progression, and to study the mortality during the period of the study. Patients and Methods: The study included 155 HIV/AIDS patients (148 HIV- infected and seven AIDS ...

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Main Authors: Ali R. Orer, Sana M.H. Alizi, Jawad K. Al-Diwan
Format: Article
Language:English
Published: College of Medicine University of Baghdad 2007-01-01
Series:مجلة كلية الطب
Subjects:
Online Access:http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1466
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author Ali R. Orer
Sana M.H. Alizi
Jawad K. Al-Diwan
author_facet Ali R. Orer
Sana M.H. Alizi
Jawad K. Al-Diwan
author_sort Ali R. Orer
collection DOAJ
description Background: The aim of the study was to determine the prevalence of CMV infection among HIV / AIDS patients in relation to disease progression, and to study the mortality during the period of the study. Patients and Methods: The study included 155 HIV/AIDS patients (148 HIV- infected and seven AIDS patients) and 122 apparently "healthy" controls. CMV (IgG and 1gM) antibodies were determined by ELISA. The patients were followed up for a period of nine months, and retested frequently for development of active CMV infection. Results: The prevalence of CMV (IgG) antibodies in the HIV/AIDS patients was 100%. A significant higher prevalence of CMV (IgM) among AIDS patients (42.9°/6) than among HIV infected patients (0.0%) and "healthy" controls (0.8%). No deaths were reported among asymptomatic HIV infected patients while the mortality among AIDS patients was (42.9%). Only one patient (7.7%) out of 13 asymptomatic HIV infected developed active CMV infection 10 years later by testing for CMV (IgM) in 1991 and 2001. Conclusion: Demonstration of active CMV is of prognostic value in detection of development of AIDS and survival of patients.
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spelling doaj.art-bd11c895a6a040c7a38d327cdd3eddbd2024-02-02T20:49:43ZengCollege of Medicine University of Baghdadمجلة كلية الطب0041-94192410-80572007-01-01484CMV infection among HIV / AIDS patients in IraqAli R. Orer0Sana M.H. Alizi1Jawad K. Al-Diwan2Center of AIDS studies and researchCentral Public health Lab., Ministry of HealthDept. Of Community Medicine, College of Medicine, Al-Anbar UniversityBackground: The aim of the study was to determine the prevalence of CMV infection among HIV / AIDS patients in relation to disease progression, and to study the mortality during the period of the study. Patients and Methods: The study included 155 HIV/AIDS patients (148 HIV- infected and seven AIDS patients) and 122 apparently "healthy" controls. CMV (IgG and 1gM) antibodies were determined by ELISA. The patients were followed up for a period of nine months, and retested frequently for development of active CMV infection. Results: The prevalence of CMV (IgG) antibodies in the HIV/AIDS patients was 100%. A significant higher prevalence of CMV (IgM) among AIDS patients (42.9°/6) than among HIV infected patients (0.0%) and "healthy" controls (0.8%). No deaths were reported among asymptomatic HIV infected patients while the mortality among AIDS patients was (42.9%). Only one patient (7.7%) out of 13 asymptomatic HIV infected developed active CMV infection 10 years later by testing for CMV (IgM) in 1991 and 2001. Conclusion: Demonstration of active CMV is of prognostic value in detection of development of AIDS and survival of patients.http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1466CMV infection among HIV / AIDS patients in Iraq
spellingShingle Ali R. Orer
Sana M.H. Alizi
Jawad K. Al-Diwan
CMV infection among HIV / AIDS patients in Iraq
مجلة كلية الطب
CMV infection among HIV / AIDS patients in Iraq
title CMV infection among HIV / AIDS patients in Iraq
title_full CMV infection among HIV / AIDS patients in Iraq
title_fullStr CMV infection among HIV / AIDS patients in Iraq
title_full_unstemmed CMV infection among HIV / AIDS patients in Iraq
title_short CMV infection among HIV / AIDS patients in Iraq
title_sort cmv infection among hiv aids patients in iraq
topic CMV infection among HIV / AIDS patients in Iraq
url http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1466
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