CMV infection among HIV / AIDS patients in Iraq
Background: The aim of the study was to determine the prevalence of CMV infection among HIV / AIDS patients in relation to disease progression, and to study the mortality during the period of the study. Patients and Methods: The study included 155 HIV/AIDS patients (148 HIV- infected and seven AIDS ...
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Format: | Article |
Language: | English |
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College of Medicine University of Baghdad
2007-01-01
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Series: | مجلة كلية الطب |
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Online Access: | http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1466 |
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author | Ali R. Orer Sana M.H. Alizi Jawad K. Al-Diwan |
author_facet | Ali R. Orer Sana M.H. Alizi Jawad K. Al-Diwan |
author_sort | Ali R. Orer |
collection | DOAJ |
description | Background: The aim of the study was to determine the prevalence of CMV infection among HIV / AIDS patients in relation to disease progression, and to study the mortality during the period of the study.
Patients and Methods: The study included 155 HIV/AIDS patients (148 HIV- infected and seven AIDS patients) and 122 apparently "healthy" controls. CMV (IgG and 1gM) antibodies were determined by ELISA. The patients were followed up for a period of nine months, and retested frequently for development of active CMV infection.
Results: The prevalence of CMV (IgG) antibodies in the HIV/AIDS patients was 100%. A significant higher prevalence of CMV (IgM) among AIDS patients (42.9°/6) than among HIV infected patients (0.0%) and "healthy" controls (0.8%). No deaths were reported among asymptomatic HIV infected patients while the mortality among AIDS patients was (42.9%). Only one patient (7.7%) out of 13 asymptomatic HIV infected developed active CMV infection 10 years later by testing for CMV (IgM) in 1991 and 2001.
Conclusion: Demonstration of active CMV is of prognostic value in detection of development of AIDS and survival of patients. |
first_indexed | 2024-03-08T07:30:28Z |
format | Article |
id | doaj.art-bd11c895a6a040c7a38d327cdd3eddbd |
institution | Directory Open Access Journal |
issn | 0041-9419 2410-8057 |
language | English |
last_indexed | 2024-03-08T07:30:28Z |
publishDate | 2007-01-01 |
publisher | College of Medicine University of Baghdad |
record_format | Article |
series | مجلة كلية الطب |
spelling | doaj.art-bd11c895a6a040c7a38d327cdd3eddbd2024-02-02T20:49:43ZengCollege of Medicine University of Baghdadمجلة كلية الطب0041-94192410-80572007-01-01484CMV infection among HIV / AIDS patients in IraqAli R. Orer0Sana M.H. Alizi1Jawad K. Al-Diwan2Center of AIDS studies and researchCentral Public health Lab., Ministry of HealthDept. Of Community Medicine, College of Medicine, Al-Anbar UniversityBackground: The aim of the study was to determine the prevalence of CMV infection among HIV / AIDS patients in relation to disease progression, and to study the mortality during the period of the study. Patients and Methods: The study included 155 HIV/AIDS patients (148 HIV- infected and seven AIDS patients) and 122 apparently "healthy" controls. CMV (IgG and 1gM) antibodies were determined by ELISA. The patients were followed up for a period of nine months, and retested frequently for development of active CMV infection. Results: The prevalence of CMV (IgG) antibodies in the HIV/AIDS patients was 100%. A significant higher prevalence of CMV (IgM) among AIDS patients (42.9°/6) than among HIV infected patients (0.0%) and "healthy" controls (0.8%). No deaths were reported among asymptomatic HIV infected patients while the mortality among AIDS patients was (42.9%). Only one patient (7.7%) out of 13 asymptomatic HIV infected developed active CMV infection 10 years later by testing for CMV (IgM) in 1991 and 2001. Conclusion: Demonstration of active CMV is of prognostic value in detection of development of AIDS and survival of patients.http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1466CMV infection among HIV / AIDS patients in Iraq |
spellingShingle | Ali R. Orer Sana M.H. Alizi Jawad K. Al-Diwan CMV infection among HIV / AIDS patients in Iraq مجلة كلية الطب CMV infection among HIV / AIDS patients in Iraq |
title | CMV infection among HIV / AIDS patients in Iraq |
title_full | CMV infection among HIV / AIDS patients in Iraq |
title_fullStr | CMV infection among HIV / AIDS patients in Iraq |
title_full_unstemmed | CMV infection among HIV / AIDS patients in Iraq |
title_short | CMV infection among HIV / AIDS patients in Iraq |
title_sort | cmv infection among hiv aids patients in iraq |
topic | CMV infection among HIV / AIDS patients in Iraq |
url | http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1466 |
work_keys_str_mv | AT alirorer cmvinfectionamonghivaidspatientsiniraq AT sanamhalizi cmvinfectionamonghivaidspatientsiniraq AT jawadkaldiwan cmvinfectionamonghivaidspatientsiniraq |