Dynamic replacement of histone H3 variants reprograms epigenetic marks in early mouse embryos.
Upon fertilization, reprogramming of gene expression is required for embryo development. This step is marked by DNA demethylation and changes in histone variant composition. However, little is known about the molecular mechanisms causing these changes and their impact on histone modifications. We ex...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2011-10-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC3188537?pdf=render |