Predicting disease-associated substitution of a single amino acid by analyzing residue interactions

<p>Abstract</p> <p>Background</p> <p>The rapid accumulation of data on non-synonymous single nucleotide polymorphisms (nsSNPs, also called SAPs) should allow us to further our understanding of the underlying disease-associated mechanisms. Here, we use complex networks t...

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Bibliographic Details
Main Authors: Yang Li, Yu Lezheng, Yin Hui, Xiao Jiamin, Wen Zhining, Li Yizhou, Li Menglong
Format: Article
Language:English
Published: BMC 2011-01-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/12/14

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