Application of natural β-glucans as biocompatible functional nanomaterials
Naturally-occurring β-glucans are mostly investigated for their antitumor activity and immunomodulatory property. They have been widely regarded as a natural source for functional foods and pharmaceuticals. However, the physico-chemically stable and biocompatible properties of β-glucans are rarely e...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Tsinghua University Press
2019-12-01
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| Series: | Food Science and Human Wellness |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213453019301442 |
| _version_ | 1797722288731193344 |
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| author | Xiaojie Li Peter Chi Keung Cheung |
| author_facet | Xiaojie Li Peter Chi Keung Cheung |
| author_sort | Xiaojie Li |
| collection | DOAJ |
| description | Naturally-occurring β-glucans are mostly investigated for their antitumor activity and immunomodulatory property. They have been widely regarded as a natural source for functional foods and pharmaceuticals. However, the physico-chemically stable and biocompatible properties of β-glucans are rarely explored as a coating material for nanomaterials to overcome the problems of aggregation and cytotoxicity. This article reviews on the exploration of β-glucans, in particular those derived from mushrooms, as a natural coating material to modify the surface properties of bioactive substances as a relatively simple and cost-effective strategy to produce stable and biocompatible nanohybrids used for biopharmaceutical use. It is envisaged that such β-glucan-based coating method will provide new opportunities to design biocompatible functional nanomaterials for wider clinical applications. Keywords: β-Glucans, Biocompatibility, Biopharmaceuticals, Nanohybrids |
| first_indexed | 2024-03-12T09:45:24Z |
| format | Article |
| id | doaj.art-bd1f3002d699459e953f5bcedcc13355 |
| institution | Directory Open Access Journal |
| issn | 2213-4530 |
| language | English |
| last_indexed | 2024-03-12T09:45:24Z |
| publishDate | 2019-12-01 |
| publisher | Tsinghua University Press |
| record_format | Article |
| series | Food Science and Human Wellness |
| spelling | doaj.art-bd1f3002d699459e953f5bcedcc133552023-09-02T12:56:55ZengTsinghua University PressFood Science and Human Wellness2213-45302019-12-0184315319Application of natural β-glucans as biocompatible functional nanomaterialsXiaojie Li0Peter Chi Keung Cheung1Food and Nutritional Sciences, School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, ChinaCorresponding author.; Food and Nutritional Sciences, School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, ChinaNaturally-occurring β-glucans are mostly investigated for their antitumor activity and immunomodulatory property. They have been widely regarded as a natural source for functional foods and pharmaceuticals. However, the physico-chemically stable and biocompatible properties of β-glucans are rarely explored as a coating material for nanomaterials to overcome the problems of aggregation and cytotoxicity. This article reviews on the exploration of β-glucans, in particular those derived from mushrooms, as a natural coating material to modify the surface properties of bioactive substances as a relatively simple and cost-effective strategy to produce stable and biocompatible nanohybrids used for biopharmaceutical use. It is envisaged that such β-glucan-based coating method will provide new opportunities to design biocompatible functional nanomaterials for wider clinical applications. Keywords: β-Glucans, Biocompatibility, Biopharmaceuticals, Nanohybridshttp://www.sciencedirect.com/science/article/pii/S2213453019301442 |
| spellingShingle | Xiaojie Li Peter Chi Keung Cheung Application of natural β-glucans as biocompatible functional nanomaterials Food Science and Human Wellness |
| title | Application of natural β-glucans as biocompatible functional nanomaterials |
| title_full | Application of natural β-glucans as biocompatible functional nanomaterials |
| title_fullStr | Application of natural β-glucans as biocompatible functional nanomaterials |
| title_full_unstemmed | Application of natural β-glucans as biocompatible functional nanomaterials |
| title_short | Application of natural β-glucans as biocompatible functional nanomaterials |
| title_sort | application of natural β glucans as biocompatible functional nanomaterials |
| url | http://www.sciencedirect.com/science/article/pii/S2213453019301442 |
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