Survival Function of the FADD-CASPASE-8-cFLIPL Complex

Survival Function of the FADD-CASPASE-8-cFLIPL Complex

Caspase-8, the initiator caspase of the death receptor pathway of apoptosis, its adapter molecule, FADD, required for caspase-8 activation, and cFLIPL, a caspase-8-like protein that lacks a catalytic site and blocks caspase-8-mediated apoptosis, are each essential for embryonic development. Animals...

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Bibliographic Details
Main Authors: Christopher P. Dillon, Andrew Oberst, Ricardo Weinlich, Laura J. Janke, Tae-Bong Kang, Tehila Ben-Moshe, Tak W. Mak, David Wallach, Douglas R. Green
Format: Article
Language:English
Published: Elsevier 2012-05-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124712000952

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