Debate: Are cluster headache and migraine distinct headache disorders?
Abstract Cluster headache and migraine are regarded as distinct primary headaches. While cluster headache and migraine differ in multiple aspects such as gender-related and headache specific features (e.g., attack duration and frequency), both show clinical similarities in trigger factors (e.g., alc...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2022-11-01
|
| Series: | The Journal of Headache and Pain |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s10194-022-01504-x |
| _version_ | 1811208066131034112 |
|---|---|
| author | Mohammad Al-Mahdi Al-Karagholi Kuan-Po Peng Anja Sofie Petersen Irene De Boer Gisela M. Terwindt Messoud Ashina |
| author_facet | Mohammad Al-Mahdi Al-Karagholi Kuan-Po Peng Anja Sofie Petersen Irene De Boer Gisela M. Terwindt Messoud Ashina |
| author_sort | Mohammad Al-Mahdi Al-Karagholi |
| collection | DOAJ |
| description | Abstract Cluster headache and migraine are regarded as distinct primary headaches. While cluster headache and migraine differ in multiple aspects such as gender-related and headache specific features (e.g., attack duration and frequency), both show clinical similarities in trigger factors (e.g., alcohol) and treatment response (e.g., triptans). Here, we review the similarities and differences in anatomy and pathophysiology that underlie cluster headache and migraine, discuss whether cluster headache and migraine should indeed be considered as two distinct primary headaches, and propose recommendations for future studies. Graphical Abstract Video recording of the debate held at the 1st International Conference on Advances in Migraine Sciences (ICAMS 2022, Copenhagen, Denmark) is available at https://www.youtube.com/watch?v=uUimmnDVTTE . |
| first_indexed | 2024-04-12T04:14:49Z |
| format | Article |
| id | doaj.art-bd26b8553863444697bac178897750ce |
| institution | Directory Open Access Journal |
| issn | 1129-2369 1129-2377 |
| language | English |
| last_indexed | 2024-04-12T04:14:49Z |
| publishDate | 2022-11-01 |
| publisher | BMC |
| record_format | Article |
| series | The Journal of Headache and Pain |
| spelling | doaj.art-bd26b8553863444697bac178897750ce2022-12-22T03:48:25ZengBMCThe Journal of Headache and Pain1129-23691129-23772022-11-0123111310.1186/s10194-022-01504-xDebate: Are cluster headache and migraine distinct headache disorders?Mohammad Al-Mahdi Al-Karagholi0Kuan-Po Peng1Anja Sofie Petersen2Irene De Boer3Gisela M. Terwindt4Messoud Ashina5Danish Headache Center, Department of Neurology, Rigshospitalet Glostrup, Faculty of Health and Medical Sciences, University of CopenhagenDepartment of Systems Neuroscience, University Medical Center Hamburg-EppendorfDanish Headache Center, Department of Neurology, Rigshospitalet Glostrup, Faculty of Health and Medical Sciences, University of CopenhagenDepartment of Neurology, Leiden University Medical CenterDepartment of Neurology, Leiden University Medical CenterDanish Headache Center, Department of Neurology, Rigshospitalet Glostrup, Faculty of Health and Medical Sciences, University of CopenhagenAbstract Cluster headache and migraine are regarded as distinct primary headaches. While cluster headache and migraine differ in multiple aspects such as gender-related and headache specific features (e.g., attack duration and frequency), both show clinical similarities in trigger factors (e.g., alcohol) and treatment response (e.g., triptans). Here, we review the similarities and differences in anatomy and pathophysiology that underlie cluster headache and migraine, discuss whether cluster headache and migraine should indeed be considered as two distinct primary headaches, and propose recommendations for future studies. Graphical Abstract Video recording of the debate held at the 1st International Conference on Advances in Migraine Sciences (ICAMS 2022, Copenhagen, Denmark) is available at https://www.youtube.com/watch?v=uUimmnDVTTE .https://doi.org/10.1186/s10194-022-01504-xCGRPNitric oxidePACAPTrigeminovascular systemCranial autonomic symptoms |
| spellingShingle | Mohammad Al-Mahdi Al-Karagholi Kuan-Po Peng Anja Sofie Petersen Irene De Boer Gisela M. Terwindt Messoud Ashina Debate: Are cluster headache and migraine distinct headache disorders? The Journal of Headache and Pain CGRP Nitric oxide PACAP Trigeminovascular system Cranial autonomic symptoms |
| title | Debate: Are cluster headache and migraine distinct headache disorders? |
| title_full | Debate: Are cluster headache and migraine distinct headache disorders? |
| title_fullStr | Debate: Are cluster headache and migraine distinct headache disorders? |
| title_full_unstemmed | Debate: Are cluster headache and migraine distinct headache disorders? |
| title_short | Debate: Are cluster headache and migraine distinct headache disorders? |
| title_sort | debate are cluster headache and migraine distinct headache disorders |
| topic | CGRP Nitric oxide PACAP Trigeminovascular system Cranial autonomic symptoms |
| url | https://doi.org/10.1186/s10194-022-01504-x |
| work_keys_str_mv | AT mohammadalmahdialkaragholi debateareclusterheadacheandmigrainedistinctheadachedisorders AT kuanpopeng debateareclusterheadacheandmigrainedistinctheadachedisorders AT anjasofiepetersen debateareclusterheadacheandmigrainedistinctheadachedisorders AT irenedeboer debateareclusterheadacheandmigrainedistinctheadachedisorders AT giselamterwindt debateareclusterheadacheandmigrainedistinctheadachedisorders AT messoudashina debateareclusterheadacheandmigrainedistinctheadachedisorders |