Does Probiotic Consumption Enhance Wound Healing? A Systematic Review
The use of probiotics is one of the emerging lines of treatment for wound healing. This systematic review aimed to summarize currently available evidence on the effect of oral or enteral probiotic therapy on skin or oral mucosal wound healing in humans. To verify the developments in this field and t...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-12-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/14/1/111 |
| _version_ | 1797498077556244480 |
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| author | Camille Togo Ana Paula Zidorio Vivian Gonçalves Patrícia Botelho Kenia de Carvalho Eliane Dutra |
| author_facet | Camille Togo Ana Paula Zidorio Vivian Gonçalves Patrícia Botelho Kenia de Carvalho Eliane Dutra |
| author_sort | Camille Togo |
| collection | DOAJ |
| description | The use of probiotics is one of the emerging lines of treatment for wound healing. This systematic review aimed to summarize currently available evidence on the effect of oral or enteral probiotic therapy on skin or oral mucosal wound healing in humans. To verify the developments in this field and the level of available scientific evidence, we applied a broad search strategy with no restrictions on wound type, target population, probiotic strain, or intervention protocol used. This review included seven studies involving 348 individuals. Four studies reported positive outcomes for healing improvement after probiotic therapy, and none of the studies reported adverse effects or a marked increase in wound healing time. The positive or neutral results observed do not generate strong evidence regarding the effectiveness of probiotics for wound healing. However, they suggest a promising field for future clinical research where the probiotic strains used, type of wounds, and target population are controlled for. |
| first_indexed | 2024-03-10T03:28:16Z |
| format | Article |
| id | doaj.art-bd2c2bbc7a8a4b5c9df02b82ea9dfbe0 |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-10T03:28:16Z |
| publishDate | 2021-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-bd2c2bbc7a8a4b5c9df02b82ea9dfbe02023-11-23T12:04:22ZengMDPI AGNutrients2072-66432021-12-0114111110.3390/nu14010111Does Probiotic Consumption Enhance Wound Healing? A Systematic ReviewCamille Togo0Ana Paula Zidorio1Vivian Gonçalves2Patrícia Botelho3Kenia de Carvalho4Eliane Dutra5Graduate Program in Human Nutrition, Faculty of Health Sciences, University of Brasilia, Campus Universitario Darcy Ribeiro, Brasilia 70910-900, BrazilGraduate Program in Human Nutrition, Faculty of Health Sciences, University of Brasilia, Campus Universitario Darcy Ribeiro, Brasilia 70910-900, BrazilGraduate Program in Public Health, Faculty of Health Sciences, University of Brasilia, Campus Universitario Darcy Ribeiro, Brasilia 70910-900, BrazilGraduate Program in Human Nutrition, Faculty of Health Sciences, University of Brasilia, Campus Universitario Darcy Ribeiro, Brasilia 70910-900, BrazilGraduate Program in Human Nutrition, Faculty of Health Sciences, University of Brasilia, Campus Universitario Darcy Ribeiro, Brasilia 70910-900, BrazilGraduate Program in Human Nutrition, Faculty of Health Sciences, University of Brasilia, Campus Universitario Darcy Ribeiro, Brasilia 70910-900, BrazilThe use of probiotics is one of the emerging lines of treatment for wound healing. This systematic review aimed to summarize currently available evidence on the effect of oral or enteral probiotic therapy on skin or oral mucosal wound healing in humans. To verify the developments in this field and the level of available scientific evidence, we applied a broad search strategy with no restrictions on wound type, target population, probiotic strain, or intervention protocol used. This review included seven studies involving 348 individuals. Four studies reported positive outcomes for healing improvement after probiotic therapy, and none of the studies reported adverse effects or a marked increase in wound healing time. The positive or neutral results observed do not generate strong evidence regarding the effectiveness of probiotics for wound healing. However, they suggest a promising field for future clinical research where the probiotic strains used, type of wounds, and target population are controlled for.https://www.mdpi.com/2072-6643/14/1/111probioticsskin woundoral mucosal woundwound healingsystematic review |
| spellingShingle | Camille Togo Ana Paula Zidorio Vivian Gonçalves Patrícia Botelho Kenia de Carvalho Eliane Dutra Does Probiotic Consumption Enhance Wound Healing? A Systematic Review Nutrients probiotics skin wound oral mucosal wound wound healing systematic review |
| title | Does Probiotic Consumption Enhance Wound Healing? A Systematic Review |
| title_full | Does Probiotic Consumption Enhance Wound Healing? A Systematic Review |
| title_fullStr | Does Probiotic Consumption Enhance Wound Healing? A Systematic Review |
| title_full_unstemmed | Does Probiotic Consumption Enhance Wound Healing? A Systematic Review |
| title_short | Does Probiotic Consumption Enhance Wound Healing? A Systematic Review |
| title_sort | does probiotic consumption enhance wound healing a systematic review |
| topic | probiotics skin wound oral mucosal wound wound healing systematic review |
| url | https://www.mdpi.com/2072-6643/14/1/111 |
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