Percutaneous endovascular biopsy for the diagnosis of pulmonary artery masses: A preliminary study of single‐center
Abstract Percutaneous endovascular biopsy (PEB) including forceps biopsy and catheter aspiration has been used to make a pretreatment diagnosis for pulmonary artery (PA) masses. This retrospective study aims to describe the procedure of PEB and compare the diagnostic yield of forceps biopsy and cath...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-04-01
|
| Series: | Pulmonary Circulation |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/pul2.12234 |
| _version_ | 1797793893668880384 |
|---|---|
| author | Cheng Hong Jie‐Long Lin Hai‐Ming Chen Wen‐Liang Guo Xiao‐Yan Li Xiao‐Feng Wu |
| author_facet | Cheng Hong Jie‐Long Lin Hai‐Ming Chen Wen‐Liang Guo Xiao‐Yan Li Xiao‐Feng Wu |
| author_sort | Cheng Hong |
| collection | DOAJ |
| description | Abstract Percutaneous endovascular biopsy (PEB) including forceps biopsy and catheter aspiration has been used to make a pretreatment diagnosis for pulmonary artery (PA) masses. This retrospective study aims to describe the procedure of PEB and compare the diagnostic yield of forceps biopsy and catheter aspiration for a definite diagnosis in patients with PA masses. All consecutive 22 patients (53 ± 14 years), 11 males and 11 females, who underwent PEB for pathologic confirmation between November 2018 and November 2022 were enrolled. All 22 patients performed computed tomography pulmonary angiography or positron emission tomography‐computed tomography to confirm the filling defects suspicious for PA malignancy before intervention. And then, all patients underwent PEB successfully without acute or fatal complications, including both forceps biopsy and catheter aspiration in 15 cases, only forceps biopsy in 5 cases, and only catheter aspiration in 2 cases. Histopathological analysis provided a definite diagnosis in all PEBs with a clinical success of 91.0% (20/22). Among them, in 15 patients who underwent both forceps biopsy and aspiration biopsy, the technical success using forceps biopsy was 93.3% (14/15), and aspiration biopsy was 6.7% (1/15), and there was a significant difference in diagnostic accuracy when comparing two techniques. Twenty‐one out of 22 PA masses (95.5%) were malignant, of which, the most frequent malignant lesion observed was PA sarcoma (66.7%, 14/21). Benign lesion included one thrombus (4.5%, 1/22). In conclusion, PEB is an effective and safe diagnostic method for differentiating benign and malignant PA masses and could be peformed when PA masses appeared clinically malignant. |
| first_indexed | 2024-03-13T02:54:51Z |
| format | Article |
| id | doaj.art-bd30f6fe6fe8425c952246a4d2df295f |
| institution | Directory Open Access Journal |
| issn | 2045-8940 |
| language | English |
| last_indexed | 2024-03-13T02:54:51Z |
| publishDate | 2023-04-01 |
| publisher | Wiley |
| record_format | Article |
| series | Pulmonary Circulation |
| spelling | doaj.art-bd30f6fe6fe8425c952246a4d2df295f2023-06-28T07:04:36ZengWileyPulmonary Circulation2045-89402023-04-01132n/an/a10.1002/pul2.12234Percutaneous endovascular biopsy for the diagnosis of pulmonary artery masses: A preliminary study of single‐centerCheng Hong0Jie‐Long Lin1Hai‐Ming Chen2Wen‐Liang Guo3Xiao‐Yan Li4Xiao‐Feng Wu5Department of Respiratory and Critical Care Medicine, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health The First Affiliated Hospital of Guangzhou Medical University Guangzhou ChinaDepartment of Radiology The First Affiliated Hospital of Guangzhou Medical University Guangzhou ChinaDepartment of Respiratory and Critical Care Medicine, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health The First Affiliated Hospital of Guangzhou Medical University Guangzhou ChinaDepartment of Respiratory and Critical Care Medicine, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health The First Affiliated Hospital of Guangzhou Medical University Guangzhou ChinaDepartment of Respiratory and Critical Care Medicine, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health The First Affiliated Hospital of Guangzhou Medical University Guangzhou ChinaDepartment of Respiratory and Critical Care Medicine, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health The First Affiliated Hospital of Guangzhou Medical University Guangzhou ChinaAbstract Percutaneous endovascular biopsy (PEB) including forceps biopsy and catheter aspiration has been used to make a pretreatment diagnosis for pulmonary artery (PA) masses. This retrospective study aims to describe the procedure of PEB and compare the diagnostic yield of forceps biopsy and catheter aspiration for a definite diagnosis in patients with PA masses. All consecutive 22 patients (53 ± 14 years), 11 males and 11 females, who underwent PEB for pathologic confirmation between November 2018 and November 2022 were enrolled. All 22 patients performed computed tomography pulmonary angiography or positron emission tomography‐computed tomography to confirm the filling defects suspicious for PA malignancy before intervention. And then, all patients underwent PEB successfully without acute or fatal complications, including both forceps biopsy and catheter aspiration in 15 cases, only forceps biopsy in 5 cases, and only catheter aspiration in 2 cases. Histopathological analysis provided a definite diagnosis in all PEBs with a clinical success of 91.0% (20/22). Among them, in 15 patients who underwent both forceps biopsy and aspiration biopsy, the technical success using forceps biopsy was 93.3% (14/15), and aspiration biopsy was 6.7% (1/15), and there was a significant difference in diagnostic accuracy when comparing two techniques. Twenty‐one out of 22 PA masses (95.5%) were malignant, of which, the most frequent malignant lesion observed was PA sarcoma (66.7%, 14/21). Benign lesion included one thrombus (4.5%, 1/22). In conclusion, PEB is an effective and safe diagnostic method for differentiating benign and malignant PA masses and could be peformed when PA masses appeared clinically malignant.https://doi.org/10.1002/pul2.12234catheter aspirationendovascular biopsyforceps biopsyintravascular filling‐defectpulmonary artery |
| spellingShingle | Cheng Hong Jie‐Long Lin Hai‐Ming Chen Wen‐Liang Guo Xiao‐Yan Li Xiao‐Feng Wu Percutaneous endovascular biopsy for the diagnosis of pulmonary artery masses: A preliminary study of single‐center Pulmonary Circulation catheter aspiration endovascular biopsy forceps biopsy intravascular filling‐defect pulmonary artery |
| title | Percutaneous endovascular biopsy for the diagnosis of pulmonary artery masses: A preliminary study of single‐center |
| title_full | Percutaneous endovascular biopsy for the diagnosis of pulmonary artery masses: A preliminary study of single‐center |
| title_fullStr | Percutaneous endovascular biopsy for the diagnosis of pulmonary artery masses: A preliminary study of single‐center |
| title_full_unstemmed | Percutaneous endovascular biopsy for the diagnosis of pulmonary artery masses: A preliminary study of single‐center |
| title_short | Percutaneous endovascular biopsy for the diagnosis of pulmonary artery masses: A preliminary study of single‐center |
| title_sort | percutaneous endovascular biopsy for the diagnosis of pulmonary artery masses a preliminary study of single center |
| topic | catheter aspiration endovascular biopsy forceps biopsy intravascular filling‐defect pulmonary artery |
| url | https://doi.org/10.1002/pul2.12234 |
| work_keys_str_mv | AT chenghong percutaneousendovascularbiopsyforthediagnosisofpulmonaryarterymassesapreliminarystudyofsinglecenter AT jielonglin percutaneousendovascularbiopsyforthediagnosisofpulmonaryarterymassesapreliminarystudyofsinglecenter AT haimingchen percutaneousendovascularbiopsyforthediagnosisofpulmonaryarterymassesapreliminarystudyofsinglecenter AT wenliangguo percutaneousendovascularbiopsyforthediagnosisofpulmonaryarterymassesapreliminarystudyofsinglecenter AT xiaoyanli percutaneousendovascularbiopsyforthediagnosisofpulmonaryarterymassesapreliminarystudyofsinglecenter AT xiaofengwu percutaneousendovascularbiopsyforthediagnosisofpulmonaryarterymassesapreliminarystudyofsinglecenter |