How to assess functional state of thyroid gland, and what should we do in situation when thyroid function tests are inadequate?

In most cases, estimation of tests of the functional state of the thyroid gland does not cause difficulties. Often, according to results of hormonal research, we can conclude that there is a manifest (subclinical) hypothyroidism or a manifest (subclinical) hyperthyroidism. In these situations, diffi...

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Main Authors: Galina A. Melnichenko, Anastasia A. Rybakova
Format: Article
Language:Russian
Published: Endocrinology Research Centre 2018-08-01
Series:Клиническая и экспериментальная тиреоидология
Subjects:
Online Access:https://cet-endojournals.ru/ket/article/viewFile/9671/7341
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author Galina A. Melnichenko
Anastasia A. Rybakova
author_facet Galina A. Melnichenko
Anastasia A. Rybakova
author_sort Galina A. Melnichenko
collection DOAJ
description In most cases, estimation of tests of the functional state of the thyroid gland does not cause difficulties. Often, according to results of hormonal research, we can conclude that there is a manifest (subclinical) hypothyroidism or a manifest (subclinical) hyperthyroidism. In these situations, difficulties in diagnosing and prescribing treatment to the patient usually do not arise. However, in clinical practice, can be a situation when the results of laboratory researches either do not correspond to clinical picture or do not correspond to the normal functioning of the pituitary-thyroid axis by the principle of log negative relationship. In such situations, quite often inadequate results can be explained by laboratory errors, effect of drugs or existence of genetic disease. Also, recently more and more questions arise in the diagnosis of the syndrome of euthyroid pathology. The correct algorithm of action in this situation will play a key role in diagnosing and identification of further tactics of patient management. In this study will be considered factors that lead to changes in laboratory researches and structured approach to assess functional state of the thyroid gland, which has big importance in clinical practice.
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spelling doaj.art-bd31aca99a7742f59cc1ca98d9473f7c2022-12-21T20:07:20ZrusEndocrinology Research CentreКлиническая и экспериментальная тиреоидология1995-54722310-37872018-08-01142869110.14341/ket96718544How to assess functional state of thyroid gland, and what should we do in situation when thyroid function tests are inadequate?Galina A. Melnichenko0Anastasia A. Rybakova1Endocrinology Research CentreEndocrinology Research CentreIn most cases, estimation of tests of the functional state of the thyroid gland does not cause difficulties. Often, according to results of hormonal research, we can conclude that there is a manifest (subclinical) hypothyroidism or a manifest (subclinical) hyperthyroidism. In these situations, difficulties in diagnosing and prescribing treatment to the patient usually do not arise. However, in clinical practice, can be a situation when the results of laboratory researches either do not correspond to clinical picture or do not correspond to the normal functioning of the pituitary-thyroid axis by the principle of log negative relationship. In such situations, quite often inadequate results can be explained by laboratory errors, effect of drugs or existence of genetic disease. Also, recently more and more questions arise in the diagnosis of the syndrome of euthyroid pathology. The correct algorithm of action in this situation will play a key role in diagnosing and identification of further tactics of patient management. In this study will be considered factors that lead to changes in laboratory researches and structured approach to assess functional state of the thyroid gland, which has big importance in clinical practice.https://cet-endojournals.ru/ket/article/viewFile/9671/7341thyroid glandthyrotropinthyroid hormone resistance syndromethyroid function teststhyrotropinoma
spellingShingle Galina A. Melnichenko
Anastasia A. Rybakova
How to assess functional state of thyroid gland, and what should we do in situation when thyroid function tests are inadequate?
Клиническая и экспериментальная тиреоидология
thyroid gland
thyrotropin
thyroid hormone resistance syndrome
thyroid function tests
thyrotropinoma
title How to assess functional state of thyroid gland, and what should we do in situation when thyroid function tests are inadequate?
title_full How to assess functional state of thyroid gland, and what should we do in situation when thyroid function tests are inadequate?
title_fullStr How to assess functional state of thyroid gland, and what should we do in situation when thyroid function tests are inadequate?
title_full_unstemmed How to assess functional state of thyroid gland, and what should we do in situation when thyroid function tests are inadequate?
title_short How to assess functional state of thyroid gland, and what should we do in situation when thyroid function tests are inadequate?
title_sort how to assess functional state of thyroid gland and what should we do in situation when thyroid function tests are inadequate
topic thyroid gland
thyrotropin
thyroid hormone resistance syndrome
thyroid function tests
thyrotropinoma
url https://cet-endojournals.ru/ket/article/viewFile/9671/7341
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AT anastasiaarybakova howtoassessfunctionalstateofthyroidglandandwhatshouldwedoinsituationwhenthyroidfunctiontestsareinadequate