Application of Supercritical Solvent Impregnation for Production of Zeolite Modified Starch-Chitosan Polymers with Antibacterial Properties
In the present study, supercritical solvent impregnation (SSI) has been applied to incorporate thymol into bio-composite polymers as a potential active packaging material. Thymol, a natural component with a proven antimicrobial activity, was successfully impregnated into starch-chitosan (SC) and sta...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-10-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/25/20/4717 |
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| author | Jelena Pajnik Ivana Lukić Jelena Dikić Jelena Asanin Milan Gordic Dusan Misic Irena Zizović Malgorzata Korzeniowska |
| author_facet | Jelena Pajnik Ivana Lukić Jelena Dikić Jelena Asanin Milan Gordic Dusan Misic Irena Zizović Malgorzata Korzeniowska |
| author_sort | Jelena Pajnik |
| collection | DOAJ |
| description | In the present study, supercritical solvent impregnation (SSI) has been applied to incorporate thymol into bio-composite polymers as a potential active packaging material. Thymol, a natural component with a proven antimicrobial activity, was successfully impregnated into starch-chitosan (SC) and starch-chitosan-zeolite (SCZ) films using supercritical carbon dioxide (scCO<sub>2</sub>) as a solvent. Experiments were performed at 35 °C, pressures of 15.5 and 30 MPa, and an impregnation time in the range of 4–24 h. The highest impregnation yields of SC films with starch to chitosan mass ratios of 1:1 and 1:2 were 10.80% and 6.48%, respectively. The addition of natural zeolite (15–60%) significantly increased the loading capacity of films enabling thymol incorporation in a quantity of 16.7–27.3%. FTIR and SEM analyses were applied for the characterization of the films. Mechanical properties and water vapor permeability of films before and after the impregnation were tested as well. Thymol release kinetics in deionized water was followed and modeled by the Korsmeyer-Peppas and Weibull model. SCZ films with thymol loading of approximately 24% exhibited strong antibacterial activity against <i>E. coli</i> and methicillin-resistant <i>Staphylococcus</i> (S.) <i>aureus</i> (MRSA). |
| first_indexed | 2024-03-10T15:37:50Z |
| format | Article |
| id | doaj.art-bd31c85e5bd64edeabca8b5e8c1f4f3d |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-10T15:37:50Z |
| publishDate | 2020-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-bd31c85e5bd64edeabca8b5e8c1f4f3d2023-11-20T17:08:30ZengMDPI AGMolecules1420-30492020-10-012520471710.3390/molecules25204717Application of Supercritical Solvent Impregnation for Production of Zeolite Modified Starch-Chitosan Polymers with Antibacterial PropertiesJelena Pajnik0Ivana Lukić1Jelena Dikić2Jelena Asanin3Milan Gordic4Dusan Misic5Irena Zizović6Malgorzata Korzeniowska7Innovation Center of the Faculty of Technology and Metallurgy, University of Belgrade, 11000 Belgrade, SerbiaFaculty of Technology and Metallurgy, University of Belgrade, 11000 Belgrade, SerbiaInnovation Center of the Faculty of Technology and Metallurgy, University of Belgrade, 11000 Belgrade, SerbiaInnovation Center of the Faculty of Technology and Metallurgy, University of Belgrade, 11000 Belgrade, SerbiaVinča Institute of Nuclear Sciences, University of Belgrade, 11351 Vinča, SerbiaFaculty of Veterinary Medicine, University of Belgrade, 11000 Belgrade, SerbiaFaculty of Chemistry, Wroclaw University of Science and Technology, 50-373 Wroclaw, PolandFaculty of Biotechnology and Food Science, Wroclaw University of Environmental and Life Sciences, 51-651 Wroclaw, PolandIn the present study, supercritical solvent impregnation (SSI) has been applied to incorporate thymol into bio-composite polymers as a potential active packaging material. Thymol, a natural component with a proven antimicrobial activity, was successfully impregnated into starch-chitosan (SC) and starch-chitosan-zeolite (SCZ) films using supercritical carbon dioxide (scCO<sub>2</sub>) as a solvent. Experiments were performed at 35 °C, pressures of 15.5 and 30 MPa, and an impregnation time in the range of 4–24 h. The highest impregnation yields of SC films with starch to chitosan mass ratios of 1:1 and 1:2 were 10.80% and 6.48%, respectively. The addition of natural zeolite (15–60%) significantly increased the loading capacity of films enabling thymol incorporation in a quantity of 16.7–27.3%. FTIR and SEM analyses were applied for the characterization of the films. Mechanical properties and water vapor permeability of films before and after the impregnation were tested as well. Thymol release kinetics in deionized water was followed and modeled by the Korsmeyer-Peppas and Weibull model. SCZ films with thymol loading of approximately 24% exhibited strong antibacterial activity against <i>E. coli</i> and methicillin-resistant <i>Staphylococcus</i> (S.) <i>aureus</i> (MRSA).https://www.mdpi.com/1420-3049/25/20/4717supercritical impregnationstarch-chitosan-zeoliteantibacterial activity |
| spellingShingle | Jelena Pajnik Ivana Lukić Jelena Dikić Jelena Asanin Milan Gordic Dusan Misic Irena Zizović Malgorzata Korzeniowska Application of Supercritical Solvent Impregnation for Production of Zeolite Modified Starch-Chitosan Polymers with Antibacterial Properties Molecules supercritical impregnation starch-chitosan-zeolite antibacterial activity |
| title | Application of Supercritical Solvent Impregnation for Production of Zeolite Modified Starch-Chitosan Polymers with Antibacterial Properties |
| title_full | Application of Supercritical Solvent Impregnation for Production of Zeolite Modified Starch-Chitosan Polymers with Antibacterial Properties |
| title_fullStr | Application of Supercritical Solvent Impregnation for Production of Zeolite Modified Starch-Chitosan Polymers with Antibacterial Properties |
| title_full_unstemmed | Application of Supercritical Solvent Impregnation for Production of Zeolite Modified Starch-Chitosan Polymers with Antibacterial Properties |
| title_short | Application of Supercritical Solvent Impregnation for Production of Zeolite Modified Starch-Chitosan Polymers with Antibacterial Properties |
| title_sort | application of supercritical solvent impregnation for production of zeolite modified starch chitosan polymers with antibacterial properties |
| topic | supercritical impregnation starch-chitosan-zeolite antibacterial activity |
| url | https://www.mdpi.com/1420-3049/25/20/4717 |
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