(2,3-Dihydro-1<i>H</i>-indol-5-ylmethyl)amine

New (2,3-dihydro-1<i>H</i>-indol-5-ylmethyl)amine was synthesized from 2-((1-acetylindolin-5-yl)methyl)isoindoline-1,3-dione by simultaneous deprotection of phthalimide and acetyl groups. The structure of the newly synthesized compounds was established by elemental analysis, high resolut...

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Bibliographic Details
Main Authors: Vladimir A. Ogurtsov, Oleg A. Rakitin
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Molbank
Subjects:
Online Access:https://www.mdpi.com/1422-8599/2021/3/M1248
Description
Summary:New (2,3-dihydro-1<i>H</i>-indol-5-ylmethyl)amine was synthesized from 2-((1-acetylindolin-5-yl)methyl)isoindoline-1,3-dione by simultaneous deprotection of phthalimide and acetyl groups. The structure of the newly synthesized compounds was established by elemental analysis, high resolution mass-spectrometry, <sup>1</sup>H, <sup>13</sup>C NMR and IR spectroscopy and mass-spectrometry. The resulting compound is a convenient intermediate for various disubstituted 1-(indolin-5-yl)methanamines, which may be of interest as substances with useful pharmacological properties.
ISSN:1422-8599