(2,3-Dihydro-1<i>H</i>-indol-5-ylmethyl)amine
New (2,3-dihydro-1<i>H</i>-indol-5-ylmethyl)amine was synthesized from 2-((1-acetylindolin-5-yl)methyl)isoindoline-1,3-dione by simultaneous deprotection of phthalimide and acetyl groups. The structure of the newly synthesized compounds was established by elemental analysis, high resolut...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-07-01
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| Series: | Molbank |
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| Online Access: | https://www.mdpi.com/1422-8599/2021/3/M1248 |
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| author | Vladimir A. Ogurtsov Oleg A. Rakitin |
| author_facet | Vladimir A. Ogurtsov Oleg A. Rakitin |
| author_sort | Vladimir A. Ogurtsov |
| collection | DOAJ |
| description | New (2,3-dihydro-1<i>H</i>-indol-5-ylmethyl)amine was synthesized from 2-((1-acetylindolin-5-yl)methyl)isoindoline-1,3-dione by simultaneous deprotection of phthalimide and acetyl groups. The structure of the newly synthesized compounds was established by elemental analysis, high resolution mass-spectrometry, <sup>1</sup>H, <sup>13</sup>C NMR and IR spectroscopy and mass-spectrometry. The resulting compound is a convenient intermediate for various disubstituted 1-(indolin-5-yl)methanamines, which may be of interest as substances with useful pharmacological properties. |
| first_indexed | 2024-03-10T07:24:28Z |
| format | Article |
| id | doaj.art-bd32289ae1144a2d8801fbde679ef4ee |
| institution | Directory Open Access Journal |
| issn | 1422-8599 |
| language | English |
| last_indexed | 2024-03-10T07:24:28Z |
| publishDate | 2021-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molbank |
| spelling | doaj.art-bd32289ae1144a2d8801fbde679ef4ee2023-11-22T14:22:24ZengMDPI AGMolbank1422-85992021-07-0120213M124810.3390/M1248(2,3-Dihydro-1<i>H</i>-indol-5-ylmethyl)amineVladimir A. Ogurtsov0Oleg A. Rakitin1N. D. Zelinsky Institute of Organic Chemistry Russian Academy of Sciences, 47 Leninsky Prospekt, 119991 Moscow, RussiaN. D. Zelinsky Institute of Organic Chemistry Russian Academy of Sciences, 47 Leninsky Prospekt, 119991 Moscow, RussiaNew (2,3-dihydro-1<i>H</i>-indol-5-ylmethyl)amine was synthesized from 2-((1-acetylindolin-5-yl)methyl)isoindoline-1,3-dione by simultaneous deprotection of phthalimide and acetyl groups. The structure of the newly synthesized compounds was established by elemental analysis, high resolution mass-spectrometry, <sup>1</sup>H, <sup>13</sup>C NMR and IR spectroscopy and mass-spectrometry. The resulting compound is a convenient intermediate for various disubstituted 1-(indolin-5-yl)methanamines, which may be of interest as substances with useful pharmacological properties.https://www.mdpi.com/1422-8599/2021/3/M12482,3-dihydroindoles (indolines)(2,3-dihydro-1<i>H</i>-indol-5-ylmethyl)aminedeprotectionbiological activity |
| spellingShingle | Vladimir A. Ogurtsov Oleg A. Rakitin (2,3-Dihydro-1<i>H</i>-indol-5-ylmethyl)amine Molbank 2,3-dihydroindoles (indolines) (2,3-dihydro-1<i>H</i>-indol-5-ylmethyl)amine deprotection biological activity |
| title | (2,3-Dihydro-1<i>H</i>-indol-5-ylmethyl)amine |
| title_full | (2,3-Dihydro-1<i>H</i>-indol-5-ylmethyl)amine |
| title_fullStr | (2,3-Dihydro-1<i>H</i>-indol-5-ylmethyl)amine |
| title_full_unstemmed | (2,3-Dihydro-1<i>H</i>-indol-5-ylmethyl)amine |
| title_short | (2,3-Dihydro-1<i>H</i>-indol-5-ylmethyl)amine |
| title_sort | 2 3 dihydro 1 i h i indol 5 ylmethyl amine |
| topic | 2,3-dihydroindoles (indolines) (2,3-dihydro-1<i>H</i>-indol-5-ylmethyl)amine deprotection biological activity |
| url | https://www.mdpi.com/1422-8599/2021/3/M1248 |
| work_keys_str_mv | AT vladimiraogurtsov 23dihydro1ihiindol5ylmethylamine AT olegarakitin 23dihydro1ihiindol5ylmethylamine |