Prenatal Diagnosis and Fetal Outcomes of Cystic Hygroma: Experience of a Tertiary Hospital
Objective: Cystic hygromas of nuchal origin are reported to be associated with fetal aneuploidy and structural anomalies in 50-80% of the cases. We aimed to report our experience on cystic hygromas via 18 cases. Study Design: We conducted a retrospective study based on a review of medical records o...
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| Format: | Article |
| Language: | English |
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Medical Network
2019-04-01
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| Series: | Gynecology Obstetrics & Reproductive Medicine |
| Subjects: | |
| Online Access: | http://gorm.com.tr/index.php/GORM/article/view/789 |
| _version_ | 1828028867423502336 |
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| author | Betul Yakistiran Doruk Cevdi Katlan Tuncay Yuce Feride Soylemez |
| author_facet | Betul Yakistiran Doruk Cevdi Katlan Tuncay Yuce Feride Soylemez |
| author_sort | Betul Yakistiran |
| collection | DOAJ |
| description | Objective: Cystic hygromas of nuchal origin are reported to be associated with fetal aneuploidy and structural anomalies in 50-80% of the cases. We aimed to report our experience on cystic hygromas via 18 cases.
Study Design: We conducted a retrospective study based on a review of medical records of patients who had fetal septated cystic hygroma, diagnosed by ultrasonography, in the Ankara University School of Medicine, Department of Obstetrics and Gynecology, between 2012 and 2016. All patients were provided with genetic counselling and prenatal invasive diagnostic procedures were applied to obtain fetal karyotype.
Results: We observed 18 cases of fetal cystic hygroma among these patients (0.39%). The abnormal karyotypes were: Turner syndrome (45X0) in 3 (16.7%), trisomy 21 in 2 (11.1%), trisomy 18 in 1 (5.6%) and mosaic Turner syndrome in 1 (5.6%) patient.
Conclusion: The presence of cystic hygroma carries a high risk for aneuploidy and major structural malformations. Invasive prenatal diagnostic procedures for fetal karyotype analyses and parental counselling about poor perinatal prognosis is mandatory. |
| first_indexed | 2024-04-10T14:01:24Z |
| format | Article |
| id | doaj.art-bd34d79a1f4d4d75b87f4a9a0732ab58 |
| institution | Directory Open Access Journal |
| issn | 1300-4751 |
| language | English |
| last_indexed | 2024-04-10T14:01:24Z |
| publishDate | 2019-04-01 |
| publisher | Medical Network |
| record_format | Article |
| series | Gynecology Obstetrics & Reproductive Medicine |
| spelling | doaj.art-bd34d79a1f4d4d75b87f4a9a0732ab582023-02-15T16:10:15ZengMedical NetworkGynecology Obstetrics & Reproductive Medicine1300-47512019-04-012514610.21613/GORM.2018.789625Prenatal Diagnosis and Fetal Outcomes of Cystic Hygroma: Experience of a Tertiary HospitalBetul Yakistiran0Doruk Cevdi Katlan1Tuncay Yuce2Feride Soylemez3Ankara University School of Medicine, Department of Obstetrics and Gynecology, AnkaraAnkara University School of Medicine, Department of Obstetrics and Gynecology, AnkaraAnkara University School of Medicine, Department of Obstetrics and Gynecology, AnkaraAnkara University School of Medicine, Department of Obstetrics and Gynecology, AnkaraObjective: Cystic hygromas of nuchal origin are reported to be associated with fetal aneuploidy and structural anomalies in 50-80% of the cases. We aimed to report our experience on cystic hygromas via 18 cases. Study Design: We conducted a retrospective study based on a review of medical records of patients who had fetal septated cystic hygroma, diagnosed by ultrasonography, in the Ankara University School of Medicine, Department of Obstetrics and Gynecology, between 2012 and 2016. All patients were provided with genetic counselling and prenatal invasive diagnostic procedures were applied to obtain fetal karyotype. Results: We observed 18 cases of fetal cystic hygroma among these patients (0.39%). The abnormal karyotypes were: Turner syndrome (45X0) in 3 (16.7%), trisomy 21 in 2 (11.1%), trisomy 18 in 1 (5.6%) and mosaic Turner syndrome in 1 (5.6%) patient. Conclusion: The presence of cystic hygroma carries a high risk for aneuploidy and major structural malformations. Invasive prenatal diagnostic procedures for fetal karyotype analyses and parental counselling about poor perinatal prognosis is mandatory.http://gorm.com.tr/index.php/GORM/article/view/789Cystic hygroma, Chromosomal disorders, Prenatal diagnosis |
| spellingShingle | Betul Yakistiran Doruk Cevdi Katlan Tuncay Yuce Feride Soylemez Prenatal Diagnosis and Fetal Outcomes of Cystic Hygroma: Experience of a Tertiary Hospital Gynecology Obstetrics & Reproductive Medicine Cystic hygroma, Chromosomal disorders, Prenatal diagnosis |
| title | Prenatal Diagnosis and Fetal Outcomes of Cystic Hygroma: Experience of a Tertiary Hospital |
| title_full | Prenatal Diagnosis and Fetal Outcomes of Cystic Hygroma: Experience of a Tertiary Hospital |
| title_fullStr | Prenatal Diagnosis and Fetal Outcomes of Cystic Hygroma: Experience of a Tertiary Hospital |
| title_full_unstemmed | Prenatal Diagnosis and Fetal Outcomes of Cystic Hygroma: Experience of a Tertiary Hospital |
| title_short | Prenatal Diagnosis and Fetal Outcomes of Cystic Hygroma: Experience of a Tertiary Hospital |
| title_sort | prenatal diagnosis and fetal outcomes of cystic hygroma experience of a tertiary hospital |
| topic | Cystic hygroma, Chromosomal disorders, Prenatal diagnosis |
| url | http://gorm.com.tr/index.php/GORM/article/view/789 |
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